Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 2038307..2039446 Replicon chromosome
Accession NZ_CP104727
Organism Pseudomonas citronellolis strain G5.80

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag N5P21_RS09085 Protein ID WP_116423098.1
Coordinates 2038676..2039446 (+) Length 257 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A1A5D9R9
Locus tag N5P21_RS09080 Protein ID WP_043271094.1
Coordinates 2038307..2038675 (+) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5P21_RS09045 (N5P21_09055) 2033500..2034336 - 837 WP_074981531.1 5'-nucleotidase, lipoprotein e(P4) family -
N5P21_RS09050 (N5P21_09060) 2034630..2035679 + 1050 WP_261747944.1 diguanylate cyclase -
N5P21_RS09055 (N5P21_09065) 2035667..2036038 - 372 WP_074981535.1 hypothetical protein -
N5P21_RS09060 (N5P21_09070) 2036130..2036471 - 342 WP_009620588.1 carboxymuconolactone decarboxylase family protein -
N5P21_RS09065 (N5P21_09075) 2036545..2037027 - 483 WP_261747945.1 GreA/GreB family elongation factor -
N5P21_RS09070 (N5P21_09080) 2037156..2037587 + 432 WP_064583930.1 hypothetical protein -
N5P21_RS09075 (N5P21_09085) 2037594..2038028 - 435 WP_074981540.1 RcnB family protein -
N5P21_RS09080 (N5P21_09090) 2038307..2038675 + 369 WP_043271094.1 DUF2384 domain-containing protein Antitoxin
N5P21_RS09085 (N5P21_09095) 2038676..2039446 + 771 WP_116423098.1 RES family NAD+ phosphorylase Toxin
N5P21_RS09090 (N5P21_09100) 2039522..2039728 + 207 WP_116423099.1 hypothetical protein -
N5P21_RS09095 (N5P21_09105) 2040252..2041616 + 1365 WP_261748738.1 DNA recombination protein RmuC -
N5P21_RS09100 (N5P21_09110) 2041938..2042825 - 888 WP_116423100.1 metal-dependent hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(69-212)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(71-120)


Sequences

Toxin        


Download         Length: 257 a.a.        Molecular weight: 28890.08 Da        Isoelectric Point: 7.0428

>T259070 WP_116423098.1 NZ_CP104727:2038676-2039446 [Pseudomonas citronellolis]
MALDVGAELWRECRGEQAIAPLRGKLVRLVESQEQVATLQLVDTLEEQALLEELIETSKPHLPPSTETLHYLLKTPFRYP
PLRWGSRFGRRHEPSLFYAALRLETAMAEAAYYRFVLWEGMASPPPSGRILSEHASFEARFQVQRGIRLQAPPFDSYAER
LQDPRDYRLTQALGSAMRAAAVEAFEYRSARCPEGGLNAALFVPSAFVDKRPRNLMPWLCETTADYVAFKHAQVPGAPRL
FPRAGFLVEGDLPHPA

Download         Length: 771 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13395.70 Da        Isoelectric Point: 10.8284

>AT259070 WP_043271094.1 NZ_CP104727:2038307-2038675 [Pseudomonas citronellolis]
MSALIRETPSADLVLAKAVLAAREQLGMTQQELAAIVGVDRSAVSRWKSGGLRVGSKTGELALLLVRVYRALFALFGGNL
EDMRHFLRTPNRHLSGVPLQRMEQVQGLVQVVEYLDAIRGKI

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1A5D9R9

References