259066

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1001374..1002041 Replicon chromosome
Accession NZ_CP104727
Organism Pseudomonas citronellolis strain G5.80

Toxin (Protein)


Gene name VapC1 Uniprot ID W5ISM6
Locus tag N5P21_RS04340 Protein ID WP_009613158.1
Coordinates 1001374..1001784 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name VapB1 Uniprot ID -
Locus tag N5P21_RS04345 Protein ID WP_253412216.1
Coordinates 1001781..1002041 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5P21_RS04320 (N5P21_04320) 997356..997889 + 534 WP_009613171.1 (2Fe-2S)-binding protein -
N5P21_RS04325 (N5P21_04325) 997892..999127 + 1236 WP_253412218.1 cytochrome c -
N5P21_RS04330 (N5P21_04330) 999129..1000097 + 969 WP_074982920.1 XdhC family protein -
N5P21_RS04335 (N5P21_04335) 1000094..1000669 + 576 WP_074982922.1 nucleotidyltransferase family protein -
N5P21_RS04340 (N5P21_04340) 1001374..1001784 - 411 WP_009613158.1 type II toxin-antitoxin system VapC family toxin Toxin
N5P21_RS04345 (N5P21_04345) 1001781..1002041 - 261 WP_253412216.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
N5P21_RS04350 (N5P21_04350) 1002124..1003248 - 1125 WP_261748720.1 class I SAM-dependent methyltransferase -
N5P21_RS04355 (N5P21_04355) 1003377..1004153 + 777 WP_061562836.1 ferredoxin--NADP reductase -
N5P21_RS04360 (N5P21_04360) 1004342..1005895 + 1554 WP_261747566.1 TerC family protein -
N5P21_RS04365 (N5P21_04365) 1005913..1006326 - 414 WP_261747567.1 large-conductance mechanosensitive channel protein MscL -
N5P21_RS04370 (N5P21_04370) 1006519..1006761 + 243 WP_074981193.1 YdcH family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-127)

Antitoxin

SpoVT-AbrB domain

(11-49)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15448.80 Da        Isoelectric Point: 7.1891

>T259066 WP_009613158.1 NZ_CP104727:c1001784-1001374 [Pseudomonas citronellolis]
VKYLLDTNILIYLLKNRPESVARRVNALPADAGLCMSFFTYAELLKGAERSTRRSEVLRQLERLTRQVPVVYDGTPRLCE
HYATQFTRLKLAGTPIGANDLWIACHALALEATLVTHNTREFERIDGLCLEDWAAE

Download         Length: 411 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9745.90 Da        Isoelectric Point: 4.2932

>AT259066 WP_253412216.1 NZ_CP104727:c1002041-1001781 [Pseudomonas citronellolis]
MSSPTLPSRVFMNGNSQAVRIPQEFRLDASRVEIRRQANGDLVIHPLPEDRGEALLQALSGFDEAFIEALEEGQREQPPM
QEREEL

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4Z0IIB3

Antitoxin

Source ID Structure

References