259065

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1(toxin)
Location 976823..977397 Replicon chromosome
Accession NZ_CP104727
Organism Pseudomonas citronellolis strain G5.80

Toxin (Protein)


Gene name vapC Uniprot ID A0A4Z0IFX5
Locus tag N5P21_RS04235 Protein ID WP_058073004.1
Coordinates 977032..977397 (+) Length 122 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID W5ISP5
Locus tag N5P21_RS04230 Protein ID WP_009613188.1
Coordinates 976823..977038 (+) Length 72 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5P21_RS04215 (N5P21_04215) 972523..973341 + 819 WP_116424330.1 ABC transporter permease subunit -
N5P21_RS04220 (N5P21_04220) 973525..974361 + 837 WP_261747561.1 taurine dioxygenase -
N5P21_RS04225 (N5P21_04225) 974730..976754 + 2025 WP_261747562.1 oligopeptide transporter, OPT family -
N5P21_RS04230 (N5P21_04230) 976823..977038 + 216 WP_009613188.1 CopG family transcriptional regulator Antitoxin
N5P21_RS04235 (N5P21_04235) 977032..977397 + 366 WP_058073004.1 type II toxin-antitoxin system VapC family toxin Toxin
N5P21_RS04240 (N5P21_04240) 977385..978110 - 726 WP_074982893.1 hypothetical protein -
N5P21_RS04245 (N5P21_04245) 978107..978289 - 183 WP_074982895.1 hypothetical protein -
N5P21_RS04250 (N5P21_04250) 978286..979434 - 1149 WP_261747563.1 PepSY domain-containing protein -
N5P21_RS04255 (N5P21_04255) 979442..981853 - 2412 WP_261747564.1 TonB-dependent receptor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-106)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-40)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 13380.44 Da        Isoelectric Point: 5.8613

>T259065 WP_058073004.1 NZ_CP104727:977032-977397 [Pseudomonas citronellolis]
MVKALFDTNILIDYLNGHEQARDELRRYDDPAISIVTWMEVMIGATPATAAATRAFLDSFALVPLDASVAERAVAVRQAL
RVKLPDAIIKASAEVQGRLLVTRNTRDFPVDDAGVRLPYRL

Download         Length: 366 bp

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 8033.94 Da        Isoelectric Point: 4.7616

>AT259065 WP_009613188.1 NZ_CP104727:976823-977038 [Pseudomonas citronellolis]
MRTLVDIPAEHLEALNALGEQQQQSRAALIREAVAEYLVRHRRQDAEAAFGLWNGSAGDGLAYQEKVREEW

Download         Length: 216 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4Z0IFX5

Antitoxin

Source ID Structure
AlphaFold DB A0A1A5D6Z2

References