Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 68616..69259 Replicon plasmid pSG.H2a_1
Accession NZ_CP104725
Organism Enterobacter kobei strain SG.H2a

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag N5P26_RS21990 Protein ID WP_261660357.1
Coordinates 68616..69032 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag N5P26_RS21995 Protein ID WP_261660358.1
Coordinates 69029..69259 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5P26_RS21985 (N5P26_21985) 67841..68584 - 744 WP_261660356.1 hypothetical protein -
N5P26_RS21990 (N5P26_21990) 68616..69032 - 417 WP_261660357.1 type II toxin-antitoxin system VapC family toxin Toxin
N5P26_RS21995 (N5P26_21995) 69029..69259 - 231 WP_261660358.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
N5P26_RS22000 (N5P26_22000) 70048..71022 + 975 WP_261660359.1 sensor domain-containing diguanylate cyclase -
N5P26_RS22005 (N5P26_22005) 71599..71892 + 294 WP_261660360.1 hypothetical protein -
N5P26_RS22010 (N5P26_22010) 71971..72678 + 708 WP_261660361.1 hypothetical protein -
N5P26_RS22015 (N5P26_22015) 72720..73463 + 744 WP_261660362.1 site-specific integrase -
N5P26_RS22020 (N5P26_22020) 73651..73920 + 270 Protein_81 site-specific integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..134081 134081


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-129)

Antitoxin

SpoVT-AbrB domain

(7-53)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15276.59 Da        Isoelectric Point: 7.7522

>T259064 WP_261660357.1 NZ_CP104725:c69032-68616 [Enterobacter kobei]
VNKTYMLDTCICSFIMREQPETVRKRLEQAVLRGNRIVISAITYQEMRFGATGPKASPRHVQLVDEFCTRLDAVLPWDRA
AVDATTDIRVALRLAGTPIGPNDTAIAGHAIAAGAVLVTNNTREFERVPGLNLEDWVK

Download         Length: 417 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8800.88 Da        Isoelectric Point: 4.2917

>AT259064 WP_261660358.1 NZ_CP104725:c69259-69029 [Enterobacter kobei]
MRTVSIFKNGNNRAIRLPRDLDFEGVSELEIVREGDSIILRPVRPTWGSFFELEKADPDFMAEREDVVSDEGRFDL

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References