Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) KacT-ataR/DUF1778(antitoxin)
Location 538232..539029 Replicon chromosome
Accession NZ_CP104691
Organism Enterobacter hormaechei strain 2022CK-00453

Toxin (Protein)


Gene name KacT Uniprot ID -
Locus tag N5934_RS02985 Protein ID WP_110870847.1
Coordinates 538232..538753 (-) Length 174 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID A0A331QJY7
Locus tag N5934_RS02990 Protein ID WP_015570876.1
Coordinates 538760..539029 (-) Length 90 a.a.

Genomic Context


N5934_RS02955N5934_RS02960N5934_RS02965N5934_RS02970N5934_RS02975N5934_RS02980N5934_RS03005N5934_RS03010N5934_RS03020N5934_RS02985N5934_RS02990N5934_RS02995N5934_RS03000N5934_RS03015N5934_RS03025
Location: 533830..534519 (690 bp)
Type: Others
Protein ID: WP_045349209.1
Location: 534531..534917 (387 bp)
Type: Others
Protein ID: WP_015570870.1
Location: 534925..535725 (801 bp)
Type: Others
Protein ID: WP_110870841.1
Location: 535735..536325 (591 bp)
Type: Others
Protein ID: WP_110870843.1
Location: 536338..536829 (492 bp)
Type: Others
Protein ID: WP_110870845.1
Location: 536851..538173 (1323 bp)
Type: Others
Protein ID: WP_047717623.1
Location: 540687..541283 (597 bp)
Type: Others
Protein ID: WP_006809323.1
Location: 541302..541529 (228 bp)
Type: Others
Protein ID: WP_006809324.1
Location: 542956..543051 (96 bp)
Type: Others
Protein ID: Protein_598
Location: 538232..538753 (522 bp)
Type: Toxin
Protein ID: WP_110870847.1
Location: 538760..539029 (270 bp)
Type: Antitoxin
Protein ID: WP_015570876.1
Location: 539103..540008 (906 bp)
Type: Others
Protein ID: WP_032653183.1
Location: 540125..540295 (171 bp)
Type: Others
Protein ID: WP_001273664.1
Location: 541562..542803 (1242 bp)
Type: Others
Protein ID: WP_047729185.1
Location: 543130..543489 (360 bp)
Type: Others
Protein ID: WP_017384779.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
N5934_RS02955 (N5934_02955)533830..534519+690WP_045349209.1pyrimidine utilization protein B-
N5934_RS02960 (N5934_02960)534531..534917+387WP_015570870.1pyrimidine utilization protein C-
N5934_RS02965 (N5934_02965)534925..535725+801WP_110870841.1pyrimidine utilization protein D-
N5934_RS02970 (N5934_02970)535735..536325+591WP_110870843.1malonic semialdehyde reductase-
N5934_RS02975 (N5934_02975)536338..536829+492WP_110870845.1pyrimidine utilization flavin reductase protein F-
N5934_RS02980 (N5934_02980)536851..538173+1323WP_047717623.1pyrimidine utilization transport protein G-
N5934_RS02985 (N5934_02985)538232..538753-522WP_110870847.1GNAT family N-acetyltransferaseToxin
N5934_RS02990 (N5934_02990)538760..539029-270WP_015570876.1DUF1778 domain-containing proteinAntitoxin
N5934_RS02995 (N5934_02995)539103..540008-906WP_032653183.1DMT family transporter-
N5934_RS03000 (N5934_03000)540125..540295-171WP_001273664.1general stress protein-
N5934_RS03005 (N5934_03005)540687..541283+597WP_006809323.1NAD(P)H:quinone oxidoreductase-
N5934_RS03010 (N5934_03010)541302..541529+228WP_006809324.1YccJ family protein-
N5934_RS03015 (N5934_03015)541562..542803-1242WP_047729185.1bifunctional glucose-1-phosphatase/inositol phosphatase-
N5934_RS03020 (N5934_03020)542956..543051+96Protein_598transcriptional regulator-
N5934_RS03025 (N5934_03025)543130..543489-360WP_017384779.1helix-turn-helix domain-containing protein-

Associated MGEs


Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(87-149)

Antitoxin

(2-88)


Sequences


Toxin        


Download         Length: 174 a.a.        Molecular weight: 19463.27 Da        Isoelectric Point: 7.4318

>T259012 WP_110870847.1 NZ_CP104691:c538753-538232 [Enterobacter hormaechei]
VANLTIEMLSEGTDYDFGDFDCGEPSLNAFLTEHLIRQHGGRILRGYLLKERDHPRVLGYYTLSGSCFEKAMLPSKIQQR
RIPYSNVPSVTLGRLAVHKELQGNEWGTTLVTHAMRVVYLASQAVGVHGIFVDALNERAKRFYLKLGFIPLAGENSSSLF
FPTQSIERLFEQA

Download         Length: 522 bp


Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10247.75 Da        Isoelectric Point: 5.8836

>AT259012 WP_015570876.1 NZ_CP104691:c539029-538760 [Enterobacter hormaechei]
MPALKKQRIDLRLSDEDKTMIEEAAAMTNQTITQFMVNSASERAAEVIEQHRRLVLNEASWIAVMDAIDNPPEPNERLKR
AAKRLRNME

Download         Length: 270 bp


Similar Proteins


Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

Loading, please wait
Source
ID
Structure
No matching records found


Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A331QJY7

References