Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2068781..2069052 Replicon chromosome
Accession NZ_CP104681
Organism Escherichia coli strain 2022CK-00450

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2068911..2069014 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2068781..2069052 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5922_RS09980 2065336..2065998 - 663 WP_000944256.1 exodeoxyribonuclease X -
N5922_RS09985 2066022..2066678 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein YobB -
N5922_RS09990 2066780..2067010 - 231 WP_000916763.1 DNA polymerase III subunit theta -
N5922_RS09995 2067149..2067523 + 375 WP_000168738.1 CopC domain-containing protein YobA -
N5922_RS10000 2067527..2068399 + 873 Protein_1953 copper homeostasis membrane protein CopD -
N5922_RS10005 2068412..2068753 + 342 WP_000976472.1 YebY family protein -
- 2068781..2069052 - 272 - - Antitoxin
- 2068911..2069014 + 104 - - Toxin
N5922_RS10010 2069149..2069805 + 657 WP_222214389.1 protein-serine/threonine phosphatase -
N5922_RS10015 2069806..2069997 - 192 WP_001313035.1 YebW family protein -
N5922_RS10020 2070102..2070338 - 237 WP_001295499.1 YebV family protein -
N5922_RS10025 2070456..2071895 - 1440 WP_024176540.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T258985 NZ_CP104681:2068911-2069014 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT258985 NZ_CP104681:c2069052-2068781 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References