Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1945122..1945267 Replicon chromosome
Accession NZ_CP104678
Organism Klebsiella pneumoniae strain 2021CK-00608

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1945158..1945260 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1945122..1945267 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5933_RS09530 1940252..1942312 + 2061 WP_004151449.1 oligopeptidase B -
N5933_RS09535 1942316..1942975 - 660 WP_020324964.1 exodeoxyribonuclease X -
N5933_RS09540 1943054..1943284 - 231 WP_002911406.1 DNA polymerase III subunit theta -
N5933_RS09545 1943397..1943771 + 375 WP_004151448.1 CopC domain-containing protein YobA -
N5933_RS09550 1943775..1944644 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
N5933_RS09555 1944661..1944999 + 339 WP_002911404.1 YebY family protein -
- 1945122..1945267 - 146 - - Antitoxin
- 1945158..1945260 + 103 - - Toxin
N5933_RS09560 1945636..1945779 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
N5933_RS09565 1945884..1946852 - 969 WP_004151446.1 VirK/YbjX family protein -
N5933_RS09570 1947009..1947662 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
N5933_RS09575 1947659..1947850 - 192 WP_002911395.1 YebW family protein -
N5933_RS09580 1947948..1948187 - 240 WP_002911393.1 YebV family protein -
N5933_RS09585 1948303..1949736 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T258963 NZ_CP104678:1945158-1945260 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT258963 NZ_CP104678:c1945267-1945122 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References