Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2194278..2194549 Replicon chromosome
Accession NZ_CP104665
Organism Escherichia coli strain 2021CK-00607

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2194408..2194511 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2194278..2194549 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5914_RS10305 2190833..2191495 - 663 WP_000944256.1 exodeoxyribonuclease X -
N5914_RS10310 2191519..2192175 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein YobB -
N5914_RS10315 2192277..2192507 - 231 WP_000916763.1 DNA polymerase III subunit theta -
N5914_RS10320 2192646..2193020 + 375 WP_022645803.1 CopC domain-containing protein YobA -
N5914_RS10325 2193024..2193896 + 873 WP_022645802.1 copper homeostasis membrane protein CopD -
N5914_RS10330 2193909..2194250 + 342 WP_000976472.1 YebY family protein -
- 2194278..2194549 - 272 - - Antitoxin
- 2194408..2194511 + 104 - - Toxin
N5914_RS10335 2194646..2195302 + 657 WP_022645801.1 protein-serine/threonine phosphatase -
N5914_RS10340 2195303..2195494 - 192 WP_001296140.1 YebW family protein -
N5914_RS10345 2195599..2195835 - 237 WP_001295499.1 YebV family protein -
N5914_RS10350 2195953..2197392 - 1440 WP_024181822.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T258917 NZ_CP104665:2194408-2194511 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT258917 NZ_CP104665:c2194549-2194278 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References