Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2061739..2061884 Replicon chromosome
Accession NZ_CP104660
Organism Klebsiella pneumoniae strain 2021CK-01729

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2061775..2061877 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2061739..2061884 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N4T33_RS09855 (N4T33_09855) 2056869..2058929 + 2061 WP_032409019.1 oligopeptidase B -
N4T33_RS09860 (N4T33_09860) 2058933..2059592 - 660 WP_002911407.1 exodeoxyribonuclease X -
N4T33_RS09865 (N4T33_09865) 2059671..2059901 - 231 WP_002911406.1 DNA polymerase III subunit theta -
N4T33_RS09870 (N4T33_09870) 2060014..2060388 + 375 WP_004151448.1 CopC domain-containing protein YobA -
N4T33_RS09875 (N4T33_09875) 2060392..2061261 + 870 WP_023316211.1 copper homeostasis membrane protein CopD -
N4T33_RS09880 (N4T33_09880) 2061278..2061616 + 339 WP_002911404.1 YebY family protein -
- 2061739..2061884 - 146 - - Antitoxin
- 2061775..2061877 + 103 - - Toxin
N4T33_RS09885 (N4T33_09885) 2062252..2062395 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
N4T33_RS09890 (N4T33_09890) 2062500..2063468 - 969 WP_004151446.1 VirK/YbjX family protein -
N4T33_RS09895 (N4T33_09895) 2063625..2064278 + 654 WP_019725444.1 protein-serine/threonine phosphatase -
N4T33_RS09900 (N4T33_09900) 2064275..2064466 - 192 WP_002911395.1 YebW family protein -
N4T33_RS09905 (N4T33_09905) 2064564..2064803 - 240 WP_002911393.1 YebV family protein -
N4T33_RS09910 (N4T33_09910) 2064919..2066352 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T258899 NZ_CP104660:2061775-2061877 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT258899 NZ_CP104660:c2061884-2061739 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References