Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 951162..951307 Replicon chromosome
Accession NZ_CP104659
Organism Klebsiella pneumoniae strain 2020CK-00096

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 951198..951300 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 951162..951307 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5936_RS04530 946292..948352 + 2061 WP_004148850.1 oligopeptidase B -
N5936_RS04535 948356..949015 - 660 WP_032435029.1 exodeoxyribonuclease X -
N5936_RS04540 949094..949324 - 231 WP_002911406.1 DNA polymerase III subunit theta -
N5936_RS04545 949437..949811 + 375 WP_004151448.1 CopC domain-containing protein YobA -
N5936_RS04550 949815..950684 + 870 WP_032435031.1 copper homeostasis membrane protein CopD -
N5936_RS04555 950701..951039 + 339 WP_002911404.1 YebY family protein -
- 951162..951307 - 146 - - Antitoxin
- 951198..951300 + 103 - - Toxin
N5936_RS04560 951675..951818 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
N5936_RS04565 951923..952891 - 969 WP_004151446.1 VirK/YbjX family protein -
N5936_RS04570 953048..953701 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
N5936_RS04575 953698..953889 - 192 WP_002911395.1 YebW family protein -
N5936_RS04580 953987..954226 - 240 WP_002911393.1 YebV family protein -
N5936_RS04585 954342..955775 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T258881 NZ_CP104659:951198-951300 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT258881 NZ_CP104659:c951307-951162 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References