Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1178838..1179109 Replicon chromosome
Accession NZ_CP104649
Organism Escherichia coli strain PNUSAE008512

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1178876..1178979 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1178838..1179109 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5913_RS06280 1175995..1177434 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
N5913_RS06285 1177552..1177788 + 237 WP_001295499.1 YebV family protein -
N5913_RS06290 1177893..1178084 + 192 WP_001296140.1 YebW family protein -
N5913_RS06295 1178085..1178741 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 1178838..1179109 + 272 - - Antitoxin
- 1178876..1178979 - 104 - - Toxin
N5913_RS06300 1179137..1179478 - 342 WP_000976483.1 YebY family protein -
N5913_RS06305 1179491..1180363 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
N5913_RS06310 1180367..1180741 - 375 WP_000168751.1 CopC domain-containing protein YobA -
N5913_RS06315 1180880..1181110 + 231 WP_000916763.1 DNA polymerase III subunit theta -
N5913_RS06320 1181212..1181868 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein YobB -
N5913_RS06325 1181892..1182554 + 663 WP_000944244.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T258848 NZ_CP104649:c1178979-1178876 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT258848 NZ_CP104649:1178838-1179109 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References