258764

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1176975..1177635 Replicon chromosome
Accession NZ_CP104643
Organism Salmonella enterica strain 1020677

Toxin (Protein)


Gene name cptA Uniprot ID Q57K70
Locus tag N5930_RS05650 Protein ID WP_000244756.1
Coordinates 1177222..1177635 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag N5930_RS05645 Protein ID WP_000351186.1
Coordinates 1176975..1177241 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5930_RS05625 (1172904) 1172904..1174337 - 1434 WP_001230141.1 6-phospho-beta-glucosidase BglA -
N5930_RS05630 (1174495) 1174495..1174806 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
N5930_RS05635 (1174970) 1174970..1175629 + 660 WP_000250289.1 hemolysin III family protein -
N5930_RS05640 (1175745) 1175745..1176725 - 981 WP_000874176.1 tRNA-modifying protein YgfZ -
N5930_RS05645 (1176975) 1176975..1177241 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
N5930_RS05650 (1177222) 1177222..1177635 + 414 WP_000244756.1 protein YgfX Toxin
N5930_RS05655 (1177688) 1177688..1178209 - 522 WP_001055885.1 flavodoxin FldB -
N5930_RS05660 (1178322) 1178322..1179218 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
N5930_RS05665 (1179242) 1179242..1179955 + 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
N5930_RS05670 (1179961) 1179961..1181694 + 1734 WP_000813389.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16183.15 Da        Isoelectric Point: 10.7537

>T258764 WP_000244756.1 NZ_CP104643:1177222-1177635 [Salmonella enterica]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT258764 WP_000351186.1 NZ_CP104643:1176975-1177241 [Salmonella enterica]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E9V5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References