Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 830587..830732 Replicon chromosome
Accession NZ_CP104638
Organism Salmonella enterica strain PNUSAS118466

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 830627..830730 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 830587..830732 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N4311_RS04930 827013..827711 - 699 WP_000944285.1 exodeoxyribonuclease X -
N4311_RS04935 827735..828391 - 657 WP_000100249.1 carbon-nitrogen hydrolase family protein -
N4311_RS04940 828499..828729 - 231 WP_000856224.1 DNA polymerase III subunit theta -
N4311_RS04945 828867..829241 + 375 WP_000168395.1 CopC domain-containing protein YobA -
N4311_RS04950 829242..830117 + 876 WP_000979684.1 copper homeostasis membrane protein CopD -
N4311_RS04955 830134..830487 + 354 WP_000722368.1 YebY family protein -
- 830587..830732 - 146 - - Antitoxin
- 830627..830730 + 104 - - Toxin
N4311_RS04960 830860..831939 - 1080 WP_000087646.1 phage integrase Arm DNA-binding domain-containing protein -
N4311_RS04965 831969..832964 - 996 Protein_788 PD-(D/E)XK nuclease-like domain-containing protein -
N4311_RS04970 833112..833360 + 249 Protein_789 glycoside hydrolase family 19 protein -
N4311_RS04975 833357..833891 + 535 Protein_790 DUF2514 domain-containing protein -
N4311_RS04980 834148..834315 - 168 WP_000789530.1 lytic enzyme -
N4311_RS04985 834380..834568 - 189 WP_001521334.1 hypothetical protein -
N4311_RS04990 834623..834883 + 261 Protein_793 DUF1441 family protein -
N4311_RS04995 835098..835442 + 345 Protein_794 macro domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 824925..870488 45563
- inside Prophage - sopE2 827013..855347 28334


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T258695 NZ_CP104638:830627-830730 [Salmonella enterica]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT258695 NZ_CP104638:c830732-830587 [Salmonella enterica]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References