Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1877338..1877483 Replicon chromosome
Accession NZ_CP104627
Organism Klebsiella pneumoniae strain AHM21C2836KI

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1877374..1877476 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1877338..1877483 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5857_RS09070 1872468..1874528 + 2061 WP_004151449.1 oligopeptidase B -
N5857_RS09075 1874532..1875191 - 660 WP_002911407.1 exodeoxyribonuclease X -
N5857_RS09080 1875270..1875500 - 231 WP_002911406.1 DNA polymerase III subunit theta -
N5857_RS09085 1875613..1875987 + 375 WP_004151448.1 CopC domain-containing protein YobA -
N5857_RS09090 1875991..1876860 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
N5857_RS09095 1876877..1877215 + 339 WP_002911404.1 YebY family protein -
- 1877338..1877483 - 146 - - Antitoxin
- 1877374..1877476 + 103 - - Toxin
N5857_RS09100 1877851..1877994 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
N5857_RS09105 1878099..1879067 - 969 WP_014907334.1 VirK/YbjX family protein -
N5857_RS09110 1879224..1879877 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
N5857_RS09115 1879874..1880065 - 192 WP_002911395.1 YebW family protein -
N5857_RS09120 1880163..1880402 - 240 WP_002911393.1 YebV family protein -
N5857_RS09125 1880518..1881951 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T258659 NZ_CP104627:1877374-1877476 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT258659 NZ_CP104627:c1877483-1877338 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References