Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/ParE-DnaT |
Location | 62950..63472 | Replicon | plasmid pHNAH8212R |
Accession | NZ_CP104615 | ||
Organism | Escherichia coli strain AHM8C212RI |
Toxin (Protein)
Gene name | relE | Uniprot ID | D0QMR1 |
Locus tag | N5856_RS24680 | Protein ID | WP_000220561.1 |
Coordinates | 62950..63231 (-) | Length | 94 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | G3CAG1 |
Locus tag | N5856_RS24685 | Protein ID | WP_000121743.1 |
Coordinates | 63221..63472 (-) | Length | 84 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
N5856_RS24650 (N5856_24580) | 58426..58662 | - | 237 | Protein_61 | hypothetical protein | - |
N5856_RS24655 (N5856_24585) | 58683..59477 | - | 795 | WP_000572405.1 | aminoglycoside O-phosphotransferase APH(3')-IIa | - |
N5856_RS24660 (N5856_24590) | 59506..60936 | - | 1431 | Protein_63 | IS4-like element IS50R family transposase | - |
N5856_RS24665 (N5856_24595) | 61056..61244 | + | 189 | WP_000957857.1 | hypothetical protein | - |
N5856_RS24670 (N5856_24600) | 61254..62453 | + | 1200 | WP_000948429.1 | IS91 family transposase | - |
N5856_RS24675 (N5856_24605) | 62619..62711 | + | 93 | Protein_66 | IS6 family transposase | - |
N5856_RS24680 (N5856_24610) | 62950..63231 | - | 282 | WP_000220561.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
N5856_RS24685 (N5856_24615) | 63221..63472 | - | 252 | WP_000121743.1 | plasmid stabilization protein | Antitoxin |
N5856_RS24690 (N5856_24620) | 64663..65502 | + | 840 | WP_024129959.1 | replication initiation protein | - |
N5856_RS24695 (N5856_24625) | 65523..66365 | + | 843 | WP_000435064.1 | replication initiation protein | - |
N5856_RS24700 (N5856_24630) | 66369..66815 | + | 447 | WP_001074384.1 | hypothetical protein | - |
N5856_RS24705 (N5856_24635) | 66952..67305 | + | 354 | WP_024129958.1 | DNA distortion polypeptide 3 | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Mobilizable plasmid | floR / tet(A) / aph(6)-Id / aph(3'')-Ib / sul2 / mph(A) / oqxA / oqxB / aph(3')-IIa / dfrA12 / aadA2 / qacE / sul1 / blaNDM-5 / rmtB / blaTEM-1B | - | 1..95335 | 95335 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3S5I302 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3S5I301 |