Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PhRel2-ATphRel2/DUF4065(antitoxin)
Location 638426..639876 Replicon
Accession NC_016784
Organism Bacillus amyloliquefaciens subsp. plantarum CAU B946

Toxin (Protein)


Gene name phRel2 Uniprot ID -
Locus tag BACAU_RS03460 Protein ID WP_014304519.1
Coordinates 638426..639115 (+) Length 230 a.a.

Antitoxin (Protein)


Gene name ATphRel2 Uniprot ID -
Locus tag BACAU_RS03465 Protein ID WP_014304520.1
Coordinates 639127..639876 (+) Length 250 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BACAU_RS03440 635918..636205 + 288 WP_014304514.1 hypothetical protein -
BACAU_RS20475 636224..636391 + 168 WP_014304515.1 XkdX family protein -
BACAU_RS03445 636405..636626 + 222 WP_014304516.1 hypothetical protein -
BACAU_RS03450 636661..637083 + 423 WP_014304517.1 phage holin family protein -
BACAU_RS03455 637130..638101 + 972 WP_014304518.1 N-acetylmuramoyl-L-alanine amidase -
BACAU_RS03460 638426..639115 + 690 WP_014304519.1 hypothetical protein Toxin
BACAU_RS03465 639127..639876 + 750 WP_014304520.1 DUF4065 domain-containing protein Antitoxin
BACAU_RS03475 640537..640896 - 360 WP_014304521.1 hypothetical protein -
BACAU_RS03480 640918..642810 - 1893 WP_014304522.1 EndoU domain-containing protein -
BACAU_RS03485 643228..643797 + 570 WP_014304523.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - groEL 597523..645410 47887


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RelA/SpoT

(100-215)

Antitoxin

Antitoxin SocA-like, Panacea domain

(113-225)


Sequences

Toxin        


Download         Length: 230 a.a.        Molecular weight: 27501.42 Da        Isoelectric Point: 8.1662

>T25861 WP_014304519.1 NC_016784:638426-639115 [Bacillus velezensis CAU B946]
MIKCTCRIESFCNHLHQLILEINQLHSDFSTNFSLKQDVKHVHLKKTQIRHVTEVTEKRNIFSIDNDFFILLQHYADKLE
DIVIYNDLEYLYSEFDLRLRVKQPDSIVNKLKYYRVGKKESGQIALRKCLNDLLGIRITIDSFDHNNKCFQDMCELLKKQ
YKINCMDSSKGDYKAFHFYFYGESTFFFPWELQIWRTDDKEANNRSHQLHKQAYKGWASIYKNSTEVEK

Download         Length: 690 bp

>T25861 NC_016784:638426-639115 [Bacillus velezensis CAU B946]
TTGATCAAATGTACTTGTCGGATTGAGTCATTTTGCAACCATCTTCATCAGTTGATACTTGAAATAAATCAGTTGCATAG
TGATTTTTCAACCAACTTCAGCTTAAAACAAGATGTAAAGCATGTTCATTTAAAAAAAACTCAAATAAGACACGTAACAG
AAGTTACAGAAAAAAGGAACATTTTCTCAATCGACAATGATTTTTTTATTTTGCTCCAACATTACGCAGATAAACTAGAA
GATATTGTCATTTATAATGACTTGGAATATCTGTACAGTGAATTTGATTTGCGGCTTAGAGTAAAACAACCAGATTCCAT
TGTCAATAAGCTTAAATATTATCGTGTGGGAAAAAAAGAAAGCGGGCAAATAGCTTTAAGAAAGTGCCTGAATGATTTGT
TGGGTATTCGAATAACAATTGACTCTTTTGACCATAATAATAAATGCTTTCAGGACATGTGTGAGTTGTTGAAAAAACAA
TACAAAATAAATTGTATGGATTCTTCCAAAGGCGACTACAAAGCATTTCATTTTTATTTTTATGGTGAGAGTACTTTTTT
CTTCCCATGGGAGCTTCAAATCTGGAGAACAGACGATAAAGAAGCGAATAATCGTTCGCATCAACTTCATAAACAAGCTT
ATAAAGGTTGGGCGTCGATTTATAAGAATTCCACAGAAGTGGAGAAGTAG

Antitoxin


Download         Length: 250 a.a.        Molecular weight: 28795.94 Da        Isoelectric Point: 6.4113

>AT25861 WP_014304520.1 NC_016784:639127-639876 [Bacillus velezensis CAU B946]
MAFHFIAIISDFSGGRRMGWHYSSEERLDKNYISDFFERVKEKCGMVQFGIHKLSTDSTSWKSVTEKDSFFDDVYVTEDI
STFIDVISKDKELTAYDVAKFVLSFKPASHLKLQKLLYYIYAEFLLKTGEKLFKEPIVAFKYGPVIESIFYKYKTHGKSE
IDYEEDASIKLRTDDVVITPSFMKILSSEYGIEALGCIIEVLVKYGRYSAFGLVEKTHQDGGPWHRVYKPGQNCVITDEL
ITQYHQHAL

Download         Length: 750 bp

>AT25861 NC_016784:639127-639876 [Bacillus velezensis CAU B946]
ATGGCATTTCATTTTATCGCGATCATTAGTGATTTTTCTGGTGGTAGAAGAATGGGCTGGCACTATTCAAGTGAAGAAAG
ATTGGATAAAAACTACATTTCCGACTTCTTTGAAAGAGTTAAAGAAAAATGTGGCATGGTTCAATTCGGAATTCACAAAC
TATCAACCGATTCAACTAGTTGGAAATCTGTAACCGAGAAAGATTCCTTTTTCGATGATGTTTATGTTACAGAAGATATT
TCAACCTTTATAGATGTGATCTCAAAAGACAAAGAACTAACCGCATATGATGTGGCGAAATTTGTCCTGTCTTTTAAACC
AGCGTCTCACTTAAAATTACAAAAACTACTTTATTATATCTATGCGGAGTTTTTGTTGAAAACAGGGGAAAAGCTATTCA
AAGAACCTATAGTAGCGTTTAAATATGGGCCAGTTATTGAGAGCATTTTCTATAAATACAAAACTCATGGCAAAAGTGAA
ATAGATTATGAAGAAGATGCTTCTATAAAGCTTCGTACAGACGATGTAGTAATAACACCTTCTTTTATGAAGATTTTATC
TTCTGAGTATGGAATTGAAGCTCTTGGATGTATTATAGAAGTTCTTGTTAAGTACGGACGATATAGTGCATTTGGTTTAG
TTGAAAAAACTCATCAAGATGGTGGGCCGTGGCATAGAGTATACAAACCAGGTCAAAATTGTGTAATAACTGATGAACTT
ATTACTCAATATCACCAACATGCGCTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References