Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1943704..1943849 Replicon chromosome
Accession NZ_CP104603
Organism Klebsiella pneumoniae strain AHM8C161BI

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1943740..1943842 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1943704..1943849 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5862_RS09655 1938834..1940894 + 2061 WP_004151449.1 oligopeptidase B -
N5862_RS09660 1940898..1941557 - 660 WP_021440386.1 exodeoxyribonuclease X -
N5862_RS09665 1941636..1941866 - 231 WP_002911406.1 DNA polymerase III subunit theta -
N5862_RS09670 1941979..1942353 + 375 WP_004151448.1 CopC domain-containing protein YobA -
N5862_RS09675 1942357..1943226 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
N5862_RS09680 1943243..1943581 + 339 WP_002911404.1 YebY family protein -
- 1943704..1943849 - 146 - - Antitoxin
- 1943740..1943842 + 103 - - Toxin
N5862_RS09685 1944218..1944361 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
N5862_RS09690 1944466..1945434 - 969 WP_004151446.1 VirK/YbjX family protein -
N5862_RS09695 1945591..1946244 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
N5862_RS09700 1946241..1946432 - 192 WP_002911395.1 YebW family protein -
N5862_RS09705 1946530..1946769 - 240 WP_002911393.1 YebV family protein -
N5862_RS09710 1946885..1948318 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1876361..1948273 71912


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T258575 NZ_CP104603:1943740-1943842 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT258575 NZ_CP104603:c1943849-1943704 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References