Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 1282023..1283425 Replicon chromosome
Accession NZ_CP104583
Organism Pseudomonas sp. GD03721

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag N5O88_RS06205 Protein ID WP_279532435.1
Coordinates 1282023..1282592 (+) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag N5O88_RS06210 Protein ID WP_279532436.1
Coordinates 1282598..1283425 (+) Length 276 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5O88_RS06200 (N5O88_06200) 1278340..1281828 - 3489 WP_147809655.1 hybrid sensor histidine kinase/response regulator -
N5O88_RS06205 (N5O88_06205) 1282023..1282592 + 570 WP_279532435.1 GNAT family protein Toxin
N5O88_RS06210 (N5O88_06210) 1282598..1283425 + 828 WP_279532436.1 AraC family transcriptional regulator Antitoxin
N5O88_RS06215 (N5O88_06215) 1284314..1285651 - 1338 WP_279532437.1 imelysin family protein -
N5O88_RS06220 (N5O88_06220) 1285842..1286414 + 573 WP_279532438.1 LemA family protein -
N5O88_RS06225 (N5O88_06225) 1286425..1287330 + 906 WP_279532439.1 GIDE domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - sodB 1153725..1353861 200136


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(14-146)

Antitoxin

DNA binding HTH domain, AraC-type

(193-270)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21394.61 Da        Isoelectric Point: 8.1211

>T258480 WP_279532435.1 NZ_CP104583:1282023-1282592 [Pseudomonas sp. GD03721]
MFKPQLVTLQRGALRLEPMADADIPALVALAEANREALLYMSGTQRLDWYRSALADLREQRALPFVIRLGDELVGTTRFA
DFMNSLPACEIGWTWLDRHQHGSGLNTSIKYLMLRHAFDHWGMVRVQLKTAASNLRAQRAIEKLGAVREGLLRNHRRLAD
GRLDDSVLFSITDHEWPALREAMEAGFGA

Download         Length: 570 bp

>T258480 NZ_CP104583:1282023-1282592 [Pseudomonas sp. GD03721]
ATGTTCAAGCCACAGTTGGTGACGTTGCAGCGTGGCGCTCTGCGCCTGGAACCCATGGCCGACGCTGACATTCCGGCGTT
GGTCGCCTTGGCCGAAGCCAATCGTGAGGCGTTGTTGTACATGAGCGGCACGCAGCGACTGGACTGGTATCGCAGCGCCC
TGGCCGACTTGCGCGAGCAGCGGGCCTTGCCTTTCGTCATTCGCCTGGGTGACGAACTGGTCGGAACCACTCGTTTCGCT
GATTTCATGAACAGCCTGCCCGCCTGCGAAATCGGCTGGACCTGGCTCGATCGTCATCAACATGGCAGCGGCCTGAATAC
CAGTATCAAGTACCTGATGCTCAGGCATGCCTTCGATCATTGGGGCATGGTTCGCGTGCAACTGAAAACCGCCGCCAGCA
ACCTGCGCGCGCAGCGCGCCATCGAGAAACTGGGTGCGGTACGCGAGGGGCTGCTGCGCAACCATCGCCGTCTGGCTGAT
GGCCGTCTCGACGATAGCGTGCTGTTCAGCATCACCGACCACGAGTGGCCGGCGCTGCGCGAGGCGATGGAGGCAGGCTT
CGGCGCCTGA

Antitoxin


Download         Length: 276 a.a.        Molecular weight: 30799.20 Da        Isoelectric Point: 8.7287

>AT258480 WP_279532436.1 NZ_CP104583:1282598-1283425 [Pseudomonas sp. GD03721]
MQTREQTRFWQASALSGVELLQARYLEQRFAPHVHEGFVFTVIEHGAQRFRHRGCDHLAPQGSMVLINPDEVHTGSKAHE
DGWRYRGFYPDNAQVLGALQELGLAKAGMPSFTFSVLHDPRLHAAFLQLHQLLEGGAEALQQQLAWREAILLLFQHHAQL
AEPPAPGREPWAVACAKQMLAERLIEPPSLEELAAAVNLSPFHFARVFRRATGLPPHAWLKQRRLEQARALLKTGCTAVA
VAMQLGFADQSHLSRQFKQVYGVSPGEYRSAVARS

Download         Length: 828 bp

>AT258480 NZ_CP104583:1282598-1283425 [Pseudomonas sp. GD03721]
ATGCAGACCCGCGAGCAGACCCGCTTCTGGCAAGCCTCCGCCTTGAGCGGAGTCGAGCTGTTGCAGGCGCGCTACCTCGA
GCAGCGTTTCGCTCCGCACGTACATGAAGGGTTCGTCTTCACCGTGATCGAGCATGGCGCCCAGCGCTTTCGCCACCGTG
GCTGCGATCATCTGGCGCCGCAGGGCAGTATGGTGCTGATCAACCCGGACGAAGTGCACACCGGCTCCAAGGCGCACGAA
GACGGCTGGCGCTATCGCGGTTTCTATCCCGACAACGCCCAGGTACTGGGAGCGCTGCAGGAACTGGGCCTGGCCAAGGC
CGGCATGCCGTCGTTTACCTTCAGCGTGCTGCATGATCCACGTTTGCATGCGGCCTTTCTGCAACTGCACCAACTGCTCG
AGGGTGGTGCTGAGGCGCTGCAGCAGCAACTGGCCTGGCGTGAGGCGATTCTGCTGCTGTTTCAGCACCATGCGCAGCTT
GCCGAACCACCTGCGCCTGGGCGTGAGCCCTGGGCAGTGGCTTGTGCCAAGCAGATGCTCGCCGAGCGGCTGATCGAGCC
GCCCTCGCTGGAGGAACTGGCGGCTGCGGTCAACCTCTCACCTTTTCACTTCGCGCGCGTATTTCGCCGCGCGACCGGCT
TGCCGCCGCATGCCTGGCTCAAACAGCGTCGCCTGGAGCAGGCGCGGGCATTGCTAAAGACGGGTTGCACGGCGGTCGCT
GTGGCGATGCAGTTGGGCTTCGCCGATCAGAGTCACTTGTCGCGACAGTTCAAGCAGGTTTATGGCGTGAGCCCTGGCGA
ATATCGCAGCGCGGTGGCCCGGAGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References