Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-stbD/ParE-DnaT
Location 18966..19533 Replicon chromosome
Accession NZ_CP104583
Organism Pseudomonas sp. GD03721

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag N5O88_RS00090 Protein ID WP_147811202.1
Coordinates 19237..19533 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID -
Locus tag N5O88_RS00085 Protein ID WP_177326260.1
Coordinates 18966..19244 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5O88_RS00065 (N5O88_00065) 14389..14919 - 531 WP_279531704.1 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase -
N5O88_RS00070 (N5O88_00070) 14977..17031 - 2055 WP_279531705.1 glycine--tRNA ligase subunit beta -
N5O88_RS00075 (N5O88_00075) 17028..18020 - 993 WP_064493650.1 glycine--tRNA ligase subunit alpha -
N5O88_RS00080 (N5O88_00080) 18193..18747 + 555 WP_143509751.1 DNA-3-methyladenine glycosylase I -
N5O88_RS00085 (N5O88_00085) 18966..19244 + 279 WP_177326260.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
N5O88_RS00090 (N5O88_00090) 19237..19533 + 297 WP_147811202.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N5O88_RS00095 (N5O88_00095) 19851..20738 + 888 WP_278618339.1 lysophospholipid acyltransferase -
N5O88_RS00100 (N5O88_00100) 21200..22540 + 1341 WP_279533131.1 group II intron reverse transcriptase/maturase -
N5O88_RS00105 (N5O88_00105) 22700..22966 + 267 WP_279531706.1 PilZ domain-containing protein -
N5O88_RS00110 (N5O88_00110) 22992..23234 - 243 Protein_21 IS5/IS1182 family transposase -
N5O88_RS00115 (N5O88_00115) 23410..24483 + 1074 Protein_22 AcvB/VirJ family lysyl-phosphatidylglycerol hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11440.46 Da        Isoelectric Point: 10.5810

>T258477 WP_147811202.1 NZ_CP104583:19237-19533 [Pseudomonas sp. GD03721]
VPSFKLEFHVKARKEWDKLDATIRLQFAKKLKERLSSPRIEADKLSGMVDCYKIKLRSAGYRLVYQVVDDKLVITVVAVG
KRERFEAYIAAQKRVQQQ

Download         Length: 297 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10058.45 Da        Isoelectric Point: 4.2457

>AT258477 WP_177326260.1 NZ_CP104583:18966-19244 [Pseudomonas sp. GD03721]
MTFPVLADVAASVTDFKRDPMGTIREGHGETVVILNRNEPAFYAVPPARYQAMLEMLDDLRLAEIVRARQGGETVSVDID
DLIAEAEAGIRA

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References