Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelE-RHH
Location 441345..441913 Replicon chromosome
Accession NZ_CP104582
Organism Pseudomonas sp. GD03919

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag N5O87_RS02060 Protein ID WP_279531965.1
Coordinates 441345..441626 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag N5O87_RS02065 Protein ID WP_279531966.1
Coordinates 441623..441913 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5O87_RS02045 (N5O87_02045) 437039..437203 - 165 Protein_406 alpha/beta hydrolase -
N5O87_RS02050 (N5O87_02050) 437205..438113 + 909 Protein_407 IS5-like element ISPa8 family transposase -
N5O87_RS02055 (N5O87_02055) 438685..441342 + 2658 WP_279531964.1 CRISPR-associated helicase Cas3' -
N5O87_RS02060 (N5O87_02060) 441345..441626 - 282 WP_279531965.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N5O87_RS02065 (N5O87_02065) 441623..441913 - 291 WP_279531966.1 hypothetical protein Antitoxin
N5O87_RS02070 (N5O87_02070) 442122..443663 + 1542 WP_279531967.1 type I-E CRISPR-associated protein Cse1/CasA -
N5O87_RS02075 (N5O87_02075) 443660..444202 + 543 WP_147810785.1 type I-E CRISPR-associated protein Cse2/CasB -
N5O87_RS02080 (N5O87_02080) 444213..445355 + 1143 WP_279531968.1 type I-E CRISPR-associated protein Cas7/Cse4/CasC -
N5O87_RS02085 (N5O87_02085) 445358..446020 + 663 WP_279531969.1 type I-E CRISPR-associated protein Cas5/CasD -
N5O87_RS02090 (N5O87_02090) 445995..446609 + 615 WP_279531970.1 type I-E CRISPR-associated protein Cas6/Cse3/CasE -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - pilT / pilU 271008..503698 232690
- flank IS/Tn - - 437208..438113 905


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10522.05 Da        Isoelectric Point: 9.6952

>T258470 WP_279531965.1 NZ_CP104582:c441626-441345 [Pseudomonas sp. GD03919]
VKLAWTRLALNDRQAIRSYIAQDNPIAALALDELFAEKAGRLADHPGLGRPGRVNGTRELVVHQHYLMIYDLANDQVRIL
RVLHTARQWPSAD

Download         Length: 282 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10848.05 Da        Isoelectric Point: 4.7266

>AT258470 WP_279531966.1 NZ_CP104582:c441913-441623 [Pseudomonas sp. GD03919]
MSEATFTFRVDDALKSEFAQAAKARDRTGAQLLRDFMRDFVRQQQEAAEHDVWLRRQVQMGLDSANAGELLSGEEVEAEA
AAWRAEMRRKLDSAAS

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References