Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 918396..918976 Replicon chromosome
Accession NZ_CP104581
Organism Delftia tsuruhatensis strain GD03927

Toxin (Protein)


Gene name vapC Uniprot ID A0A072T5F9
Locus tag N5O86_RS04140 Protein ID WP_016448367.1
Coordinates 918396..918776 (-) Length 127 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A072THC0
Locus tag N5O86_RS04145 Protein ID WP_016448366.1
Coordinates 918773..918976 (-) Length 68 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5O86_RS04120 (N5O86_04120) 913707..914948 + 1242 WP_016448371.1 ABC transporter substrate-binding protein -
N5O86_RS04125 (N5O86_04125) 914945..915703 + 759 WP_026062833.1 ABC transporter permease -
N5O86_RS04130 (N5O86_04130) 915750..917336 - 1587 WP_279494191.1 Ig-like domain repeat protein -
N5O86_RS04135 (N5O86_04135) 917566..918318 + 753 WP_234640264.1 helix-turn-helix transcriptional regulator -
N5O86_RS04140 (N5O86_04140) 918396..918776 - 381 WP_016448367.1 PIN domain-containing protein Toxin
N5O86_RS04145 (N5O86_04145) 918773..918976 - 204 WP_016448366.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
N5O86_RS04150 (N5O86_04150) 919127..919939 + 813 WP_083393616.1 glucose 1-dehydrogenase -
N5O86_RS04155 (N5O86_04155) 920049..921722 + 1674 WP_279494195.1 VRR-NUC domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-114)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-43)


Sequences

Toxin        


Download         Length: 127 a.a.        Molecular weight: 13790.24 Da        Isoelectric Point: 8.3155

>T258464 WP_016448367.1 NZ_CP104581:c918776-918396 [Delftia tsuruhatensis]
MNPVLVDTSVWIDHFRQGNPHLAQLLQQDMALMHPLVLGELACGTPPARARTLADLQRLKPARQASMREVLALIEREQLF
GLGCGLVDITLLASALMSSGASLWSLDKRLHALAQRFGIACRSVLP

Download         Length: 381 bp

Antitoxin


Download         Length: 68 a.a.        Molecular weight: 7499.60 Da        Isoelectric Point: 4.5702

>AT258464 WP_016448366.1 NZ_CP104581:c918976-918773 [Delftia tsuruhatensis]
MRTTVTIDDALYEEALELAEPEMDKADLFREAIKTFVRVQAAKRLAALGGSAPDMREIPRRPQGIEP

Download         Length: 204 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A072T5F9

Antitoxin

Source ID Structure
AlphaFold DB A0A072THC0

References