Detailed information of TA system TA258461

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 79615..81071
• Replicon: chromosome
• Accession: NZ_CP104581
• Organism: Delftia tsuruhatensis strain GD03927

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: N5O86_RS00345
• Protein ID: WP_279493791.1
• Coordinates: 79615..80460 (-)
• Length: 282 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: N5O86_RS00350
• Protein ID: WP_016447321.1
• Coordinates: 80457..81071 (-)
• Length: 205 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
N5O86_RS00320 (N5O86_00320)	74976..76139	+	1164	WP_016447315.1	ABC transporter substrate-binding protein	-
N5O86_RS00325 (N5O86_00325)	76182..77054	+	873	WP_017405698.1	branched-chain amino acid ABC transporter permease	-
N5O86_RS00330 (N5O86_00330)	77058..78125	+	1068	WP_279493790.1	branched-chain amino acid ABC transporter permease	-
N5O86_RS00335 (N5O86_00335)	78118..78876	+	759	WP_071953933.1	ABC transporter ATP-binding protein	-
N5O86_RS00340 (N5O86_00340)	78881..79582	+	702	WP_017405695.1	ABC transporter ATP-binding protein	-
N5O86_RS00345 (N5O86_00345)	79615..80460	-	846	WP_279493791.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
N5O86_RS00350 (N5O86_00350)	80457..81071	-	615	WP_016447321.1	AbiEi antitoxin N-terminal domain-containing protein	Antitoxin
N5O86_RS00355 (N5O86_00355)	81179..81652	-	474	WP_012202024.1	hotdog fold thioesterase	-
N5O86_RS00360 (N5O86_00360)	81775..83289	-	1515	WP_279493792.1	acetyl-CoA hydrolase/transferase family protein	-
N5O86_RS00365 (N5O86_00365)	83497..84804	-	1308	WP_046239355.1	solute carrier family 23 protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (35-258)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (12-57)

Sequences

Toxin

Protein

• Length: 282 a.a.
• Molecular weight: 31029.70 Da
• Isoelectric Point: 7.2651

>T258461 WP_279493791.1 NZ_CP104581:c80460-79615 [Delftia tsuruhatensis]
MSRDIVASIRARLKQCADARRQDFNLTLTHYGLERLLYRLSISPHADSYLLKGALLFAIWYEQPHRPTRDADLLGFGLDD
VDSAVSAFREICGIAVDDGIAFDAASVRGTAIRKEAGYGGVRIDLRATLDGARITLQVDIGFGDAVTPSPQTIRYPVLLD
GLPAPQLRSYPKYTVVAEKLHAICLLGMANTRMKDYFDLWVLMTEGTLDPAELRRAMAATFERRQLALPAGLPAGLSDGF
SSDAAKQAQWAAFLKKNRLEALELAPVVARLREEFQQCGIF

Nucleotide

• Length: 846 bp

Antitoxin

Protein

• Length: 205 a.a.
• Molecular weight: 21967.59 Da
• Isoelectric Point: 9.9117

>AT258461 WP_016447321.1 NZ_CP104581:c81071-80457 [Delftia tsuruhatensis]
MPAPGSALEQAVLALAEQRPLLRARDLAALGLPTMALSRLVAAGRLERVARGLYSLPGRPLSEHRSLAEVALRVPQGVVC
LLSALRVHGIGTQAPFEVWMAIPHHSPTPRIDQPALRAIRMSGAALSEGVETLQIDGVGVAVFNASKTVADCFKYRNKIG
LDVALEALRDGWAQRKLTADALWHYAAIDRVSNVMRPYLESIAA

Nucleotide

• Length: 615 bp