Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 4513122..4513624 Replicon chromosome
Accession NZ_CP104579
Organism Pseudomonas oleovorans strain GD04132

Toxin (Protein)


Gene name yoeB Uniprot ID W6RLX6
Locus tag N5O83_RS21870 Protein ID WP_003464804.1
Coordinates 4513122..4513376 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID W6R1F7
Locus tag N5O83_RS21875 Protein ID WP_003464807.1
Coordinates 4513373..4513624 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5O83_RS21845 (N5O83_21840) 4508659..4508982 - 324 Protein_4286 TraR/DksA C4-type zinc finger protein -
N5O83_RS21850 (N5O83_21845) 4509084..4509968 + 885 WP_279534066.1 GTP cyclohydrolase FolE2 -
N5O83_RS21855 (N5O83_21850) 4510075..4511994 + 1920 WP_279534067.1 DUF294 nucleotidyltransferase-like domain-containing protein -
N5O83_RS21860 (N5O83_21855) 4511991..4512698 + 708 WP_279534068.1 3'-5' exonuclease -
N5O83_RS21865 (N5O83_21860) 4512760..4512921 + 162 WP_003464802.1 DUF2986 domain-containing protein -
N5O83_RS21870 (N5O83_21865) 4513122..4513376 - 255 WP_003464804.1 Txe/YoeB family addiction module toxin Toxin
N5O83_RS21875 (N5O83_21870) 4513373..4513624 - 252 WP_003464807.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
N5O83_RS21880 (N5O83_21875) 4513779..4514681 - 903 WP_003464809.1 LysR family transcriptional regulator -
N5O83_RS21885 (N5O83_21880) 4514865..4516253 + 1389 WP_003464812.1 L-serine ammonia-lyase -
N5O83_RS21890 (N5O83_21885) 4516609..4518276 - 1668 WP_279534069.1 BCCT family transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10268.83 Da        Isoelectric Point: 9.8757

>T258458 WP_003464804.1 NZ_CP104579:c4513376-4513122 [Pseudomonas oleovorans]
VNLVFSEQAWADYLYWQGQDKKTLKRINELLKEIKRTPFEGMGKPEPLKHALAGYWSRRINEEHRLVYRLREHEILIAQV
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9255.54 Da        Isoelectric Point: 4.5535

>AT258458 WP_003464807.1 NZ_CP104579:c4513624-4513373 [Pseudomonas oleovorans]
MDAITYSTARANLANTMDRVCEDHEPIIITRNGQQAVVMMSLDDYKALEETAYLLRSPKNAQRLLESIAALETGKGVTRE
LDL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB W6RLX6

Antitoxin

Source ID Structure
AlphaFold DB W6R1F7

References