258457

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelE-RHH
Location 3785348..3785916 Replicon chromosome
Accession NZ_CP104579
Organism Pseudomonas oleovorans strain GD04132

Toxin (Protein)


Gene name parE Uniprot ID W6QTT6
Locus tag N5O83_RS18455 Protein ID WP_004424733.1
Coordinates 3785635..3785916 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID W6RBZ2
Locus tag N5O83_RS18450 Protein ID WP_004424730.1
Coordinates 3785348..3785638 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5O83_RS18420 (N5O83_18415) 3780404..3781066 - 663 WP_004424717.1 type I-E CRISPR-associated protein Cas5/CasD -
N5O83_RS18425 (N5O83_18420) 3781069..3782211 - 1143 WP_004424719.1 type I-E CRISPR-associated protein Cas7/Cse4/CasC -
N5O83_RS18430 (N5O83_18425) 3782222..3782764 - 543 WP_004424722.1 type I-E CRISPR-associated protein Cse2/CasB -
N5O83_RS18435 (N5O83_18430) 3782761..3784296 - 1536 WP_004424723.1 type I-E CRISPR-associated protein Cse1/CasA -
N5O83_RS18440 (N5O83_18435) 3784406..3784831 - 426 WP_084340296.1 type II toxin-antitoxin system VapC family toxin -
N5O83_RS18445 (N5O83_18440) 3784831..3785082 - 252 WP_004424728.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
N5O83_RS18450 (N5O83_18445) 3785348..3785638 + 291 WP_004424730.1 hypothetical protein Antitoxin
N5O83_RS18455 (N5O83_18450) 3785635..3785916 + 282 WP_004424733.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
N5O83_RS18460 (N5O83_18455) 3785919..3788576 - 2658 WP_279533820.1 CRISPR-associated helicase Cas3' -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10565.07 Da        Isoelectric Point: 8.6765

>T258457 WP_004424733.1 NZ_CP104579:3785635-3785916 [Pseudomonas oleovorans]
VKLAWTRLALNDRQAIRSYIAQDNPIATLALDELFTEKASRLADHPGLGRPGRVSGTRELVVHQHDLMIYDLVNDQVRIL
RVLHTARQWPSAD

Download         Length: 282 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10878.08 Da        Isoelectric Point: 4.7266

>AT258457 WP_004424730.1 NZ_CP104579:3785348-3785638 [Pseudomonas oleovorans]
MSEATFTFRVDDALKSEFAQAAKARDRTGAQLLRDFMRDFVRQQQEAAEHDVWLRRQVQMGLDSANAGELLSSEEVEAEA
AAWRAEMRRKLDSAAS

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB W6QTT6

Antitoxin

Source ID Structure
AlphaFold DB W6RBZ2

References