258455

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 3383573..3384780 Replicon chromosome
Accession NZ_CP104579
Organism Pseudomonas oleovorans strain GD04132

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag N5O83_RS16520 Protein ID WP_206409045.1
Coordinates 3383573..3384325 (-) Length 251 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID W6QTC2
Locus tag N5O83_RS16525 Protein ID WP_003462583.1
Coordinates 3384409..3384780 (-) Length 124 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5O83_RS16505 (N5O83_16500) 3380382..3381335 + 954 WP_279533709.1 alpha/beta fold hydrolase -
N5O83_RS16510 (N5O83_16505) 3381343..3382704 - 1362 WP_162884251.1 DNA recombination protein RmuC -
N5O83_RS16515 (N5O83_16510) 3382884..3383135 - 252 WP_017675070.1 sel1 repeat family protein -
N5O83_RS16520 (N5O83_16515) 3383573..3384325 - 753 WP_206409045.1 RES family NAD+ phosphorylase Toxin
N5O83_RS16525 (N5O83_16520) 3384409..3384780 - 372 WP_003462583.1 XRE family transcriptional regulator Antitoxin
N5O83_RS16530 (N5O83_16525) 3384913..3387468 + 2556 WP_084340548.1 YdbH domain-containing protein -
N5O83_RS16535 (N5O83_16530) 3387473..3387664 + 192 WP_003462588.1 YnbE family lipoprotein -
N5O83_RS16540 (N5O83_16535) 3387696..3388034 + 339 WP_003462591.1 YdbL family protein -
N5O83_RS16545 (N5O83_16540) 3388780..3389106 - 327 WP_003246056.1 Grx4 family monothiol glutaredoxin -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(62-206)

Antitoxin

(72-121)


Sequences


Toxin        


Download         Length: 251 a.a.        Molecular weight: 28533.58 Da        Isoelectric Point: 7.8844

>T258455 WP_206409045.1 NZ_CP104579:c3384325-3383573 [Pseudomonas oleovorans]
MDIWQLCDGERQVRPLRGKLLRMVESQAQVATLQLVDNLAEQTLLEELLESSKPPLPEAAEPLHYLLKTPFRYPPLRWGS
RFGRVHEPSLFYAAQRLQTAMAEAAYYRFVLWNGMVVPPPSGRILSEHSTFEARYRVEHGIQLQQSPFAQHDALLAHPSD
YSVPRRLGTSMRAAGIQAFEYRSARCPDGGSNVALYVPAAFVEKRPRNLTAWLCETTSEYVAFKHAQTPDQPRLFHWEQF
LVQGQLPHPA

Download         Length: 753 bp


Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13661.73 Da        Isoelectric Point: 10.6604

>AT258455 WP_003462583.1 NZ_CP104579:c3384780-3384409 [Pseudomonas oleovorans]
MSAVTRSQPDADAVLAKALLNTREQLGLTQQELADIVGVHRSAISRWSEQGGLRPQSKTGELALLLIRAYRALFALFGGN
QQDMRHFLRTENRHLAGIPLQQMSQVQGLVRVVEYLDAIRGKV

Download         Length: 372 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB W6QTC2

References