Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 3374841..3376243 Replicon chromosome
Accession NZ_CP104579
Organism Pseudomonas oleovorans strain GD04132

Toxin (Protein)


Gene name - Uniprot ID W6QUR4
Locus tag N5O83_RS16495 Protein ID WP_003462563.1
Coordinates 3375674..3376243 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A2W5WET3
Locus tag N5O83_RS16490 Protein ID WP_039964860.1
Coordinates 3374841..3375668 (-) Length 276 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5O83_RS16475 (N5O83_16470) 3370926..3371831 - 906 WP_279533706.1 GIDE domain-containing protein -
N5O83_RS16480 (N5O83_16475) 3371842..3372414 - 573 WP_013716744.1 LemA family protein -
N5O83_RS16485 (N5O83_16480) 3372605..3373942 + 1338 WP_279533707.1 imelysin family protein -
N5O83_RS16490 (N5O83_16485) 3374841..3375668 - 828 WP_039964860.1 AraC family transcriptional regulator Antitoxin
N5O83_RS16495 (N5O83_16490) 3375674..3376243 - 570 WP_003462563.1 GNAT family protein Toxin
N5O83_RS16500 (N5O83_16495) 3376446..3379934 + 3489 WP_279533708.1 PAS domain-containing hybrid sensor histidine kinase/response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(14-146)

Antitoxin

AraC-type arabinose-binding/dimerisation domain

(17-142)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21497.72 Da        Isoelectric Point: 8.9246

>T258454 WP_003462563.1 NZ_CP104579:c3376243-3375674 [Pseudomonas oleovorans]
MFKPQLVTLQRGALRLEPLSDADIPALVALAEANREELLYMSGTQRLDWYRSALADMREQRALPFVIRLGNEWVGTTRFA
DFMNPLPACEIGWTWLDRNQHGSGLNTSIKYLMLKHAFENWGMVRVQLKTAASNLRSQRAIEKLGAVREGLLRNHRRLAD
GRLDDTVLYSITDLEWPALRGAMEAGFNA

Download         Length: 570 bp

Antitoxin


Download         Length: 276 a.a.        Molecular weight: 30840.23 Da        Isoelectric Point: 8.3478

>AT258454 WP_039964860.1 NZ_CP104579:c3375668-3374841 [Pseudomonas oleovorans]
MHSREQTRFWQASALSGVELLQARYLEQRFAPHVHEGFVFTVIEHGAQRFRHRGCDHLAPQGSMVLINPDEVHTGSKAHE
DGWRYRGFYPDNAQVLGALQELGLAKAGMPSFAFSVLHDPRLHAAFLQLHQLLEGGAEALQQQLAWREAMLLLFQHHAQL
AEPPAPGREPWAVACAKQMLAERLIEPPSLEELAAAVNLSPFHFARVFRRETGLPPHAWLKQRRLEQARALLKTGCTAVA
VAMQLGFADQSHLSRQFKQVYGVSPGEYRSAVARS

Download         Length: 828 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB W6QUR4

Antitoxin

Source ID Structure
AlphaFold DB A0A2W5WET3

References