258448

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 747997..748538 Replicon chromosome
Accession NZ_CP104579
Organism Pseudomonas oleovorans strain GD04132

Toxin (Protein)


Gene name relE Uniprot ID A0A379JU38
Locus tag N5O83_RS03500 Protein ID WP_074856108.1
Coordinates 747997..748293 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A379JUV6
Locus tag N5O83_RS03505 Protein ID WP_074856106.1
Coordinates 748281..748538 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5O83_RS03480 (N5O83_03485) 743995..745002 + 1008 WP_279534397.1 cytochrome d ubiquinol oxidase subunit II -
N5O83_RS03485 (N5O83_03490) 745013..745159 + 147 WP_279534398.1 DUF2474 domain-containing protein -
N5O83_RS03490 (N5O83_03495) 745232..746674 + 1443 WP_279534399.1 TldD/PmbA family protein -
N5O83_RS03495 (N5O83_03500) 746674..747993 + 1320 Protein_694 metallopeptidase TldD-related protein -
N5O83_RS03500 (N5O83_03505) 747997..748293 - 297 WP_074856108.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N5O83_RS03505 (N5O83_03510) 748281..748538 - 258 WP_074856106.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
N5O83_RS03510 (N5O83_03515) 748608..749732 - 1125 WP_004425056.1 class I SAM-dependent methyltransferase -
N5O83_RS03515 (N5O83_03520) 749976..750752 + 777 WP_279534400.1 ferredoxin--NADP reductase -
N5O83_RS03520 (N5O83_03525) 750753..751778 - 1026 WP_004425051.1 hemolysin family protein -
N5O83_RS03525 (N5O83_03530) 752019..752267 + 249 WP_004425048.1 YdcH family protein -
N5O83_RS03530 (N5O83_03535) 752336..752614 + 279 WP_279534401.1 DUF465 domain-containing protein -
N5O83_RS03535 (N5O83_03540) 752876..753352 - 477 WP_279534402.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11418.23 Da        Isoelectric Point: 6.0752

>T258448 WP_074856108.1 NZ_CP104579:c748293-747997 [Pseudomonas oleovorans]
MAEIVWTNTALEQLDDLAHYIALDKPDAARALVRRAVETVSRLADFPLSGRVPDELPHSVYREIVIPPCRIFYRYTDTTV
FIIHIMREERVLRAHMLE

Download         Length: 297 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9800.29 Da        Isoelectric Point: 7.3183

>AT258448 WP_074856106.1 NZ_CP104579:c748538-748281 [Pseudomonas oleovorans]
MKVELVTNLKRQATKILADLHESKEPVLITEHGMPSAYLVDVDDYQFMQRRLALLDALARGERAVIEGNTQNHEQAKERL
SKWLK

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A379JU38

Antitoxin

Source ID Structure
AlphaFold DB A0A379JUV6

References