Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 2882024..2882802 Replicon chromosome
Accession NZ_CP104562
Organism Roseateles sp. BIM B-1768

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag N4261_RS12175 Protein ID WP_261760398.1
Coordinates 2882024..2882506 (-) Length 161 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag N4261_RS12180 Protein ID WP_261760399.1
Coordinates 2882533..2882802 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N4261_RS12155 (N4261_12175) 2877440..2878396 - 957 WP_261760395.1 xanthine dehydrogenase family protein subunit M -
N4261_RS12160 (N4261_12180) 2878393..2879040 - 648 WP_261760694.1 aldehyde dehydrogenase iron-sulfur subunit PaoA -
N4261_RS12165 (N4261_12185) 2879492..2879674 - 183 WP_261760396.1 DUF3606 domain-containing protein -
N4261_RS12170 (N4261_12190) 2879789..2881879 - 2091 WP_261760397.1 diguanylate cyclase -
N4261_RS12175 (N4261_12195) 2882024..2882506 - 483 WP_261760398.1 GNAT family N-acetyltransferase Toxin
N4261_RS12180 (N4261_12200) 2882533..2882802 - 270 WP_261760399.1 DUF1778 domain-containing protein Antitoxin
N4261_RS12185 (N4261_12205) 2883112..2884221 + 1110 WP_261760400.1 NAD(P)/FAD-dependent oxidoreductase -
N4261_RS12190 (N4261_12210) 2884417..2886399 - 1983 WP_261760401.1 RecQ family ATP-dependent DNA helicase -
N4261_RS12195 (N4261_12215) 2886733..2886888 + 156 WP_261760402.1 DUF3309 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(38-137)

Antitoxin

Vibrio phage ICP1, Orf50

(8-82)


Sequences

Toxin        


Download         Length: 161 a.a.        Molecular weight: 16797.29 Da        Isoelectric Point: 8.5093

>T258446 WP_261760398.1 NZ_CP104562:c2882506-2882024 [Roseateles sp. BIM B-1768]
MITAAHDCSAFTCTHTPLTDWLQRRALPNQAAGASRTYVVSTSDQQVVGYYALAPGAVAADATPGALRRNMPQPIPVFVL
GRLAVHSAWQGLGIGSGLLRDAVLRSAEAAQIVGGRALLCHSIDEQAKGFYCKHGFVQSPMEPLTVMLGLKASSTAPPNA

Download         Length: 483 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9963.21 Da        Isoelectric Point: 4.6750

>AT258446 WP_261760399.1 NZ_CP104562:c2882802-2882533 [Roseateles sp. BIM B-1768]
MTASTTTINFRATTDFRDLIDRAATAQGKTRTDFIMAASEAEAQRVLLDRAFFQLDEAQMQAFQAVLDQPIDQNAAVNRL
LAKKAPWDQ

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References