Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 75277..75857 Replicon chromosome
Accession NZ_CP104562
Organism Roseateles sp. BIM B-1768

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N4261_RS00310 Protein ID WP_261758214.1
Coordinates 75480..75857 (+) Length 126 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N4261_RS00305 Protein ID WP_261758213.1
Coordinates 75277..75483 (+) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N4261_RS00285 (N4261_00285) 70941..72290 - 1350 WP_261760854.1 pyridoxal-phosphate dependent enzyme -
N4261_RS00290 (N4261_00290) 72726..73556 + 831 WP_261758210.1 ABC transporter substrate-binding protein -
N4261_RS00295 (N4261_00295) 73720..74421 + 702 WP_261758211.1 amino acid ABC transporter permease -
N4261_RS00300 (N4261_00300) 74432..75112 + 681 WP_261758212.1 amino acid ABC transporter permease -
N4261_RS00305 (N4261_00305) 75277..75483 + 207 WP_261758213.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
N4261_RS00310 (N4261_00310) 75480..75857 + 378 WP_261758214.1 PIN domain-containing protein Toxin
N4261_RS00315 (N4261_00315) 75877..76845 - 969 WP_261758215.1 ABC transporter permease subunit -
N4261_RS00320 (N4261_00320) 76842..77783 - 942 WP_261758216.1 ABC transporter ATP-binding protein -
N4261_RS00325 (N4261_00325) 77891..78853 - 963 WP_261760855.1 ABC transporter substrate-binding protein -
N4261_RS00330 (N4261_00330) 78898..79869 - 972 WP_261758217.1 TauD/TfdA family dioxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-112)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 13769.29 Da        Isoelectric Point: 7.2449

>T258445 WP_261758214.1 NZ_CP104562:75480-75857 [Roseateles sp. BIM B-1768]
MNIVVDTSVWIDFFRAGNDRLLHLLDADVVLAHPMIIGELACGTPRSPRTASLSMLRRLGLSRAVAMEEVLRLVEQEKLY
GKGCGLVDMVVLASTLKTPGAVLWSLDKRLTLLAEQFQIAMPSVH

Download         Length: 378 bp

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7597.78 Da        Isoelectric Point: 4.4013

>AT258445 WP_261758213.1 NZ_CP104562:75277-75483 [Roseateles sp. BIM B-1768]
MEMTIMIDEALYREALEVVGRPMPVDELVTTALRTFIRVEAGRRLAALGGTAPDMPDIPRRREAPDES

Download         Length: 207 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References