Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | TsdAT/- |
Location | 2176204..2176718 | Replicon | chromosome |
Accession | NZ_CP104559 | ||
Organism | Staphylococcus aureus strain SA2107 |
Toxin (Protein)
Gene name | TsdT | Uniprot ID | A0A0U1MQX5 |
Locus tag | N4T05_RS10925 | Protein ID | WP_000581795.1 |
Coordinates | 2176204..2176413 (-) | Length | 70 a.a. |
Antitoxin (Protein)
Gene name | TsdA | Uniprot ID | A0A0U1MQV0 |
Locus tag | N4T05_RS10930 | Protein ID | WP_000138930.1 |
Coordinates | 2176425..2176718 (-) | Length | 98 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
N4T05_RS10905 (2171711) | 2171711..2173069 | - | 1359 | WP_234739929.1 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase | - |
N4T05_RS10910 (2173084) | 2173084..2174154 | - | 1071 | WP_000159641.1 | D-alanine--D-alanine ligase | - |
N4T05_RS10915 (2174472) | 2174472..2175674 | + | 1203 | WP_001109939.1 | FtsW/RodA/SpoVE family cell cycle protein | - |
N4T05_RS10920 (2175939) | 2175939..2176076 | - | 138 | WP_000828354.1 | Lmo0850 family protein | - |
N4T05_RS10925 (2176204) | 2176204..2176413 | - | 210 | WP_000581795.1 | heavy metal-associated domain-containing protein | Toxin |
N4T05_RS10930 (2176425) | 2176425..2176718 | - | 294 | WP_000138930.1 | copper-sensing transcriptional repressor CsoR | Antitoxin |
N4T05_RS10935 (2176884) | 2176884..2178368 | + | 1485 | WP_000571562.1 | cardiolipin synthase | - |
N4T05_RS10940 (2178396) | 2178396..2179043 | + | 648 | WP_001187625.1 | HD domain-containing protein | - |
N4T05_RS10945 (2179593) | 2179593..2180465 | - | 873 | WP_000725802.1 | membrane protein insertase YidC | - |
N4T05_RS10950 (2180551) | 2180551..2181192 | - | 642 | WP_000483162.1 | thiamine phosphate synthase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0U1MQX5 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0U1MQV0 |