Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-DUF971
Location 5112579..5113177 Replicon chromosome
Accession NZ_CP104557
Organism Pseudomonas promysalinigenes strain RL-WG26

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag N5C08_RS23695 Protein ID WP_186476156.1
Coordinates 5112875..5113177 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag N5C08_RS23690 Protein ID WP_261744407.1
Coordinates 5112579..5112878 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5C08_RS23670 (N5C08_23670) 5108481..5108849 - 369 WP_261744406.1 hypothetical protein -
N5C08_RS23675 (N5C08_23675) 5109026..5109715 + 690 WP_003253341.1 phosphate regulon transcriptional regulator PhoB -
N5C08_RS23680 (N5C08_23680) 5109764..5111071 + 1308 WP_060477252.1 phosphate regulon sensor histidine kinase PhoR -
N5C08_RS23685 (N5C08_23685) 5111199..5112539 + 1341 WP_060477253.1 hemolysin family protein -
N5C08_RS23690 (N5C08_23690) 5112579..5112878 - 300 WP_261744407.1 putative addiction module antidote protein Antitoxin
N5C08_RS23695 (N5C08_23695) 5112875..5113177 - 303 WP_186476156.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N5C08_RS23700 (N5C08_23700) 5113219..5114121 - 903 WP_261744408.1 M23 family metallopeptidase -
N5C08_RS23705 (N5C08_23705) 5114236..5115135 - 900 WP_060477257.1 response regulator -
N5C08_RS23710 (N5C08_23710) 5115300..5116070 - 771 WP_207936634.1 phosphate signaling complex protein PhoU -
N5C08_RS23715 (N5C08_23715) 5116225..5117058 - 834 WP_261744409.1 phosphate ABC transporter ATP-binding protein PstB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-95)

Antitoxin

Uncharacterized protein HI1420

(6-90)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11351.89 Da        Isoelectric Point: 10.3124

>T258435 WP_186476156.1 NZ_CP104557:c5113177-5112875 [Pseudomonas promysalinigenes]
MKSIKQTATYRNWERKLRDKQARAIIAARVFRLAHGLLGDVQPVGQGISELRIHHGPGYRIYYQQRGNQLVLLLCGGDKS
SQSRDIETAKSLASQWSDDE

Download         Length: 303 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10774.23 Da        Isoelectric Point: 5.6863

>AT258435 WP_261744407.1 NZ_CP104557:c5112878-5112579 [Pseudomonas promysalinigenes]
MKEQFYDYDPAEALTDAESIAIFMEDAFETGDAAYIAQALGVVARAKGMTTIATEAGVSREHLYRSFSAKGNPTLKTMLA
VMRAVGLDLTSRRHSKPAQ

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References