258433

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 336071..336575 Replicon chromosome
Accession NZ_CP104557
Organism Pseudomonas promysalinigenes strain RL-WG26

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag N5C08_RS01565 Protein ID WP_261745578.1
Coordinates 336351..336575 (+) Length 75 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A5R8Z7Y5
Locus tag N5C08_RS01560 Protein ID WP_060478286.1
Coordinates 336071..336310 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5C08_RS01545 (N5C08_01545) 331294..332676 - 1383 WP_261744554.1 ATP-binding protein -
N5C08_RS01550 (N5C08_01550) 332678..333397 - 720 WP_261744555.1 response regulator transcription factor -
N5C08_RS01555 (N5C08_01555) 333537..335834 + 2298 WP_261744556.1 TonB-dependent siderophore receptor -
N5C08_RS01560 (N5C08_01560) 336071..336310 + 240 WP_060478286.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
N5C08_RS01565 (N5C08_01565) 336351..336575 + 225 WP_261745578.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N5C08_RS01570 (N5C08_01570) 336516..336839 - 324 WP_060478289.1 helix-turn-helix domain-containing protein -
N5C08_RS01575 (N5C08_01575) 336970..337173 + 204 Protein_304 type II toxin-antitoxin system RelB/DinJ family antitoxin -
N5C08_RS01580 (N5C08_01580) 337587..338600 + 1014 WP_261744557.1 hypothetical protein -
N5C08_RS01585 (N5C08_01585) 338611..339228 + 618 WP_261744559.1 NADAR family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-62)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-70)


Sequences

Toxin        


Download         Length: 75 a.a.        Molecular weight: 8411.72 Da        Isoelectric Point: 10.4329

>T258433 WP_261745578.1 NZ_CP104557:336351-336575 [Pseudomonas promysalinigenes]
MGDTVRQQLKRKLASVLLNPRVEANRLDSLPNGYKIKLRSSGYRLIYQVVDQEETSEVLRVAARQFYALAGIGF

Download         Length: 225 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9082.47 Da        Isoelectric Point: 4.6182

>AT258433 WP_060478286.1 NZ_CP104557:336071-336310 [Pseudomonas promysalinigenes]
MASINVRIDDDLKIRAYRELERLGVTPSELMRQALQYVAERGQLPFKPVLMTDEDEALLATVRERLADPQRVKVSLDDL

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A5R8Z7Y5

References