Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3284990..3285135 Replicon chromosome
Accession NZ_CP104551
Organism Klebsiella pneumoniae strain K28074

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3284997..3285099 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3284990..3285135 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5911_RS16615 (N5911_16615) 3280522..3281955 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
N5911_RS16620 (N5911_16620) 3282071..3282310 + 240 WP_002911393.1 YebV family protein -
N5911_RS16625 (N5911_16625) 3282408..3282599 + 192 WP_002911395.1 YebW family protein -
N5911_RS16630 (N5911_16630) 3282596..3283249 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
N5911_RS16635 (N5911_16635) 3283406..3284374 + 969 WP_004151446.1 VirK/YbjX family protein -
N5911_RS16640 (N5911_16640) 3284479..3284622 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3284990..3285135 + 146 - - Antitoxin
- 3284997..3285099 - 103 - - Toxin
N5911_RS16645 (N5911_16645) 3285258..3285596 - 339 WP_002911404.1 YebY family protein -
N5911_RS16650 (N5911_16650) 3285613..3286482 - 870 WP_062955019.1 copper homeostasis membrane protein CopD -
N5911_RS16655 (N5911_16655) 3286486..3286860 - 375 WP_004151448.1 CopC domain-containing protein YobA -
N5911_RS16660 (N5911_16660) 3286973..3287203 + 231 WP_002911406.1 DNA polymerase III subunit theta -
N5911_RS16665 (N5911_16665) 3287282..3287941 + 660 WP_002911407.1 exodeoxyribonuclease X -
N5911_RS16670 (N5911_16670) 3287945..3290005 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T258415 NZ_CP104551:c3285099-3284997 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT258415 NZ_CP104551:3284990-3285135 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References