Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1985459..1985730 Replicon chromosome
Accession NZ_CP104536
Organism Escherichia coli strain E3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1985589..1985692 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1985459..1985730 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5O72_RS09600 1982014..1982676 - 663 WP_000944256.1 exodeoxyribonuclease X -
N5O72_RS09605 1982700..1983356 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
N5O72_RS09610 1983458..1983688 - 231 WP_000916763.1 DNA polymerase III subunit theta -
N5O72_RS09615 1983827..1984201 + 375 WP_000204699.1 CopC domain-containing protein YobA -
N5O72_RS09620 1984205..1985077 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
N5O72_RS09625 1985090..1985431 + 342 WP_000976492.1 YebY family protein -
- 1985459..1985730 - 272 - - Antitoxin
- 1985589..1985692 + 104 - - Toxin
N5O72_RS09630 1985827..1986483 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
N5O72_RS09635 1986484..1986675 - 192 WP_001296140.1 YebW family protein -
N5O72_RS09640 1986780..1987016 - 237 WP_001295499.1 YebV family protein -
N5O72_RS09645 1987134..1988573 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T258356 NZ_CP104536:1985589-1985692 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT258356 NZ_CP104536:c1985730-1985459 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References