Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2219990..2220258 Replicon chromosome
Accession NZ_CP104533
Organism Escherichia coli strain E10

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2220118..2220220 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2219990..2220258 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5O77_RS10855 2216544..2217206 - 663 WP_000944256.1 exodeoxyribonuclease X -
N5O77_RS10860 2217229..2217885 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
N5O77_RS10865 2217987..2218217 - 231 WP_000916763.1 DNA polymerase III subunit theta -
N5O77_RS10870 2218356..2218730 + 375 WP_000168747.1 CopC domain-containing protein YobA -
N5O77_RS10875 2218734..2219606 + 873 WP_000879320.1 copper homeostasis membrane protein CopD -
N5O77_RS10880 2219619..2219960 + 342 WP_000984819.1 YebY family protein -
- 2219990..2220258 - 269 - - Antitoxin
- 2220118..2220220 + 103 - - Toxin
N5O77_RS10885 2220355..2221011 + 657 WP_000812741.1 protein-serine/threonine phosphatase -
N5O77_RS10890 2221012..2221203 - 192 WP_001296140.1 YebW family protein -
N5O77_RS10895 2221308..2221544 - 237 WP_001295499.1 YebV family protein -
N5O77_RS10900 2221662..2223101 - 1440 WP_261175610.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T258323 NZ_CP104533:2220118-2220220 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT258323 NZ_CP104533:c2220258-2219990 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References