Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2060641..2060912 Replicon chromosome
Accession NZ_CP104526
Organism Escherichia coli strain E8

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2060771..2060874 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2060641..2060912 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5O73_RS10025 2057196..2057858 - 663 WP_063078890.1 exodeoxyribonuclease X -
N5O73_RS10030 2057882..2058538 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein YobB -
N5O73_RS10035 2058640..2058870 - 231 WP_000916763.1 DNA polymerase III subunit theta -
N5O73_RS10040 2059009..2059383 + 375 WP_000168747.1 CopC domain-containing protein YobA -
N5O73_RS10045 2059387..2060259 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
N5O73_RS10050 2060272..2060613 + 342 WP_000976476.1 YebY family protein -
- 2060641..2060912 - 272 - - Antitoxin
- 2060771..2060874 + 104 - - Toxin
N5O73_RS10055 2061009..2061665 + 657 WP_000812720.1 protein-serine/threonine phosphatase -
N5O73_RS10060 2061666..2061857 - 192 WP_001296140.1 YebW family protein -
N5O73_RS10065 2061962..2062198 - 237 WP_001295499.1 YebV family protein -
N5O73_RS10070 2062316..2063755 - 1440 WP_024176540.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T258302 NZ_CP104526:2060771-2060874 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT258302 NZ_CP104526:c2060912-2060641 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References