Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2520144..2520412 Replicon chromosome
Accession NZ_CP104521
Organism Escherichia coli strain E5

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2520182..2520284 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2520144..2520412 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5O78_RS12235 2517301..2518740 + 1440 WP_001317885.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
N5O78_RS12240 2518858..2519094 + 237 WP_001295499.1 YebV family protein -
N5O78_RS12245 2519199..2519390 + 192 WP_001317886.1 YebW family protein -
N5O78_RS12250 2519391..2520047 - 657 WP_000812744.1 protein-serine/threonine phosphatase -
- 2520144..2520412 + 269 - - Antitoxin
- 2520182..2520284 - 103 - - Toxin
N5O78_RS12255 2520442..2520783 - 342 WP_000976472.1 YebY family protein -
N5O78_RS12260 2520796..2521668 - 873 WP_000879316.1 copper homeostasis membrane protein CopD -
N5O78_RS12265 2521672..2522046 - 375 WP_000168747.1 CopC domain-containing protein YobA -
N5O78_RS12270 2522185..2522415 + 231 WP_000916759.1 DNA polymerase III subunit theta -
N5O78_RS12275 2522517..2523173 + 657 WP_000011673.1 carbon-nitrogen hydrolase family protein YobB -
N5O78_RS12280 2523197..2523859 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences

Toxin        


Download         Length: 103 bp

>T258246 NZ_CP104521:c2520284-2520182 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT258246 NZ_CP104521:2520144-2520412 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures

Antitoxin

Download structure file

Antitoxin

Download structure file

References