Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2803284..2803518 Replicon chromosome
Accession NZ_CP104500
Organism Escherichia coli strain E9

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2803285..2803388 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2803284..2803518 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5O75_RS13805 2800232..2801284 + 1053 WP_001004419.1 RecT family recombinase -
N5O75_RS13810 2801348..2801542 + 195 WP_071780718.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
N5O75_RS13815 2801535..2801723 + 189 WP_001356607.1 DUF1187 family protein -
- 2801541..2801719 - 179 NuclAT_0 - -
- 2801541..2801719 - 179 NuclAT_0 - -
- 2801541..2801719 - 179 NuclAT_0 - -
- 2801541..2801719 - 179 NuclAT_0 - -
N5O75_RS13820 2801830..2802111 + 282 WP_001311878.1 excisionase -
N5O75_RS13825 2802077..2803153 + 1077 WP_001189087.1 phage integrase Arm DNA-binding domain-containing protein -
- 2803284..2803518 + 235 - - Antitoxin
- 2803285..2803388 - 104 - - Toxin
N5O75_RS13830 2803546..2803887 - 342 WP_000976492.1 YebY family protein -
N5O75_RS13835 2803900..2804772 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
N5O75_RS13840 2804776..2805150 - 375 WP_000204700.1 CopC domain-containing protein YobA -
N5O75_RS13845 2805289..2805519 + 231 WP_000916763.1 DNA polymerase III subunit theta -
N5O75_RS13850 2805621..2806277 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
N5O75_RS13855 2806301..2806963 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2745439..2809020 63581


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T258141 NZ_CP104500:c2803388-2803285 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT258141 NZ_CP104500:2803284-2803518 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References