Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 7797..8332 Replicon plasmid unnamed1
Accession NZ_CP104485
Organism Salmonella enterica strain SalSpp_sample_07_No.3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag N4231_RS24365 Protein ID WP_032206513.1
Coordinates 7797..8084 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID T1PXV2
Locus tag N4231_RS24370 Protein ID WP_001139206.1
Coordinates 8081..8332 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N4231_RS24350 (N4231_24350) 3422..6937 + 3516 WP_072752622.1 autotransporter outer membrane beta-barrel domain-containing protein -
N4231_RS24355 (N4231_24355) 7112..7317 - 206 Protein_5 hypothetical protein -
N4231_RS24360 (N4231_24360) 7316..7429 + 114 Protein_6 alkaline phosphatase -
N4231_RS24365 (N4231_24365) 7797..8084 - 288 WP_032206513.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N4231_RS24370 (N4231_24370) 8081..8332 - 252 WP_001139206.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
N4231_RS24375 (N4231_24375) 8992..12881 + 3890 Protein_9 helicase-related protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Mobilizable plasmid ant(3'')-Ia / lnu(F) / aac(3)-IId / blaTEM-1B / tet(A) - 1..82631 82631


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11130.20 Da        Isoelectric Point: 10.5833

>T258092 WP_032206513.1 NZ_CP104485:c8084-7797 [Salmonella enterica]
MTYTVKFRDDALKEWLRLDKTIQQQFAKKLKKCSENPHIASAKLRGLKDCYKIKLRASGFRLVYQIIDDMLIIAVVAVGK
RERSNVYHLASERMK

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9171.39 Da        Isoelectric Point: 4.0927

>AT258092 WP_001139206.1 NZ_CP104485:c8332-8081 [Salmonella enterica]
MPSIILSDTSASVSELKKNPMATVSAGEGYPVAILNRNQPAFYCVPAELYERMLDALDDQELVKLVTERSSQPLHDVDLD
SYL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB T1PXV2

References