Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 841011..841671 Replicon chromosome
Accession NZ_CP104482
Organism Salmonella enterica strain SalSpp_sample_08_No.4

Toxin (Protein)


Gene name cptA Uniprot ID A0A5I5GR00
Locus tag N4230_RS04040 Protein ID WP_000244761.1
Coordinates 841258..841671 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag N4230_RS04035 Protein ID WP_000351186.1
Coordinates 841011..841277 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N4230_RS04015 (836940) 836940..838373 - 1434 WP_080192298.1 6-phospho-beta-glucosidase BglA -
N4230_RS04020 (838531) 838531..838842 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
N4230_RS04025 (839006) 839006..839665 + 660 WP_000250289.1 hemolysin III family protein -
N4230_RS04030 (839781) 839781..840761 - 981 WP_023193393.1 tRNA-modifying protein YgfZ -
N4230_RS04035 (841011) 841011..841277 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
N4230_RS04040 (841258) 841258..841671 + 414 WP_000244761.1 protein YgfX Toxin
N4230_RS04045 (841724) 841724..842245 - 522 WP_001055885.1 flavodoxin FldB -
N4230_RS04050 (842358) 842358..843254 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
N4230_RS04055 (843278) 843278..843991 + 714 WP_080192297.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
N4230_RS04060 (843997) 843997..845730 + 1734 WP_000813387.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16199.15 Da        Isoelectric Point: 10.7537

>T258059 WP_000244761.1 NZ_CP104482:841258-841671 [Salmonella enterica]
VVLWQSDLRVSWRAQWISLLIHGLVSAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT258059 WP_000351186.1 NZ_CP104482:841011-841277 [Salmonella enterica]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5I5GR00

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References