258038

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 90128..90795 Replicon chromosome
Accession NZ_CP104479
Organism Salmonella enterica strain SalSpp_sample_09_No.5

Toxin (Protein)


Gene name ypjF Uniprot ID A0A745GLG6
Locus tag N4G50_RS00440 Protein ID WP_024156847.1
Coordinates 90128..90448 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag N4G50_RS00445 Protein ID WP_023181597.1
Coordinates 90469..90795 (-) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N4G50_RS00425 (87773) 87773..88390 - 618 WP_000984812.1 helix-turn-helix transcriptional regulator -
N4G50_RS00430 (89147) 89147..89257 - 111 Protein_85 IS3 family transposase -
N4G50_RS00435 (89638) 89638..89965 + 328 Protein_86 transposase -
N4G50_RS00440 (90128) 90128..90448 - 321 WP_024156847.1 TA system toxin CbtA family protein Toxin
N4G50_RS00445 (90469) 90469..90795 - 327 WP_023181597.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
N4G50_RS00450 (90808) 90808..91278 - 471 WP_015703840.1 DNA repair protein RadC -
N4G50_RS00455 (91347) 91347..92168 - 822 WP_023181598.1 DUF932 domain-containing protein -
N4G50_RS00460 (92240) 92240..92689 - 450 WP_023181599.1 hypothetical protein -
N4G50_RS00465 (92933) 92933..93736 - 804 WP_023181600.1 hypothetical protein -
N4G50_RS00470 (93756) 93756..94190 - 435 WP_023181601.1 hypothetical protein -
N4G50_RS00475 (94589) 94589..95743 - 1155 WP_233592746.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 89120..105610 16490
- flank IS/Tn - - 89120..89257 137


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-98)

Antitoxin

Antitoxin CbeA

(7-107)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12066.80 Da        Isoelectric Point: 5.0482

>T258038 WP_024156847.1 NZ_CP104479:c90448-90128 [Salmonella enterica]
MNTQPATTPQAAKPCLSPLAVWQMLLTSLLDQHYGLTLNDTPFSDETVIQKHIEAGITLADAVNFLVERYELVRIDQKGF
SVQDQEPWLTSMDVHRARFKLNVERL

Download         Length: 321 bp

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12353.05 Da        Isoelectric Point: 5.8083

>AT258038 WP_023181597.1 NZ_CP104479:c90795-90469 [Salmonella enterica]
MSLISAHEWGLQREIVPRFGARLVQEGNRLHYLADRANLMGIFSDTECFKLDDAFPHFISQMESMLTTGELIPCHHHCVT
LYHNDFTCEADTLGSCGYVYIAVYPTQR

Download         Length: 327 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A745GLG6

Antitoxin

Source ID Structure

References