Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 653226..653497 Replicon chromosome
Accession NZ_CP104472
Organism Escherichia coli strain UC4224

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 653264..653367 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 653226..653497 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N4S17_RS03195 650383..651822 + 1440 WP_028985418.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
N4S17_RS03200 651940..652176 + 237 WP_001295499.1 YebV family protein -
N4S17_RS03205 652281..652472 + 192 WP_001296140.1 YebW family protein -
N4S17_RS03210 652473..653129 - 657 WP_000812734.1 protein-serine/threonine phosphatase -
- 653226..653497 + 272 - - Antitoxin
- 653264..653367 - 104 - - Toxin
N4S17_RS03215 653525..653866 - 342 WP_000976492.1 YebY family protein -
N4S17_RS03220 653879..654751 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
N4S17_RS03225 654755..655129 - 375 WP_000204699.1 CopC domain-containing protein YobA -
N4S17_RS03230 655268..655498 + 231 WP_000916763.1 DNA polymerase III subunit theta -
N4S17_RS03235 655600..656256 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
N4S17_RS03240 656280..656942 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T257990 NZ_CP104472:c653367-653264 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT257990 NZ_CP104472:653226-653497 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References