257975

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 939523..940238 Replicon chromosome
Accession NZ_CP104471
Organism Enterobacter hormaechei strain 80014967

Toxin (Protein)


Gene name ypjF Uniprot ID A0A8I0UM05
Locus tag NYP10_RS05650 Protein ID WP_023303149.1
Coordinates 939870..940238 (+) Length 123 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag NYP10_RS05645 Protein ID WP_180242253.1
Coordinates 939523..939849 (+) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYP10_RS05620 (NYP10_05620) 934557..935822 + 1266 WP_023303143.1 hypothetical protein -
NYP10_RS05625 (NYP10_05625) 936131..936565 + 435 WP_023303144.1 hypothetical protein -
NYP10_RS05630 (NYP10_05630) 936624..937463 + 840 WP_023303145.1 hypothetical protein -
NYP10_RS05635 (NYP10_05640) 938153..938974 + 822 WP_023303146.1 DUF932 domain-containing protein -
NYP10_RS05640 (NYP10_05645) 939040..939510 + 471 WP_023303147.1 DNA repair protein RadC -
NYP10_RS05645 (NYP10_05650) 939523..939849 + 327 WP_180242253.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
NYP10_RS05650 (NYP10_05655) 939870..940238 + 369 WP_023303149.1 TA system toxin CbtA family protein Toxin
NYP10_RS05655 (NYP10_05660) 941004..941162 + 159 WP_023315491.1 hypothetical protein -
NYP10_RS05660 (NYP10_05665) 941268..941810 + 543 WP_032608608.1 type IV secretion protein Rhs -
NYP10_RS05665 (NYP10_05670) 941813..942169 + 357 WP_032608610.1 hypothetical protein -
NYP10_RS05670 (NYP10_05675) 942192..942383 - 192 WP_071785715.1 YecR family lipoprotein -
NYP10_RS05675 (NYP10_05680) 942376..943574 + 1199 WP_136780082.1 IS3 family transposase -
NYP10_RS05680 (NYP10_05685) 943681..944427 - 747 WP_045344151.1 class I SAM-dependent methyltransferase -
NYP10_RS05685 (NYP10_05690) 944438..944695 - 258 WP_003863178.1 YjhX family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 918605..943574 24969


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-111)

Antitoxin

Antitoxin CbeA

(7-107)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13727.91 Da        Isoelectric Point: 8.2822

>T257975 WP_023303149.1 NZ_CP104471:939870-940238 [Enterobacter hormaechei]
MKNLPATISRAAKPCLSPVAVWQMLLTRLLEQHYGLTLNDTPFSDETVIKEHIDAGIILADAVNFLVDKYELVRIDRRGF
SSQGQVPYLTVTDILHARRACGLMKSCSYREVSNIVLSHSRQ

Download         Length: 369 bp

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12206.03 Da        Isoelectric Point: 6.9463

>AT257975 WP_180242253.1 NZ_CP104471:939523-939849 [Enterobacter hormaechei]
MSLIPAQEWGIKSDIVPRLGVRLVQEGNRLHYLADRASITGKFSDAECLKLDIVFPHFIRQMESMLTTGEMNSRHAHCVT
LYHNGFTCEADTLGSCGYVYIAIYPTQR

Download         Length: 327 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References