Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemK-mazE/MazF(toxin)
Location 6598085..6598690 Replicon chromosome
Accession NZ_CP104467
Organism Paenibacillus sp. SS4

Toxin (Protein)


Gene name pemK Uniprot ID A0A1V4HIK6
Locus tag NYR53_RS29515 Protein ID WP_028553893.1
Coordinates 6598085..6598435 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag NYR53_RS29520 Protein ID WP_157318061.1
Coordinates 6598439..6598690 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYR53_RS29495 6593140..6593493 + 354 WP_261302611.1 hydrolase/acyltransferase -
NYR53_RS29500 6593664..6593828 + 165 WP_090818813.1 cortex morphogenetic protein CmpA -
NYR53_RS29505 6594263..6594979 + 717 WP_261302612.1 hypothetical protein -
NYR53_RS29510 6595676..6597919 - 2244 WP_261306569.1 Tex family protein -
NYR53_RS29515 6598085..6598435 - 351 WP_028553893.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
NYR53_RS29520 6598439..6598690 - 252 WP_157318061.1 ribbon-helix-helix protein, CopG family Antitoxin
NYR53_RS29525 6598946..6600136 - 1191 WP_261302613.1 alanine racemase -
NYR53_RS29530 6600219..6601559 - 1341 WP_261302614.1 SEC-C metal-binding domain-containing protein -
NYR53_RS29535 6601731..6602912 - 1182 WP_261302615.1 outer membrane lipoprotein-sorting protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-110)

Antitoxin

Ribbon-helix-helix protein, CopG

(2-36)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12860.75 Da        Isoelectric Point: 4.8837

>T257970 WP_028553893.1 NZ_CP104467:c6598435-6598085 [Paenibacillus sp. SS4]
VIVKRGDVFFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAETHGFDRDSVILLEQI
RTIDKQRLTDKITHLDEETMRKVDDALQISVGLIEF

Download         Length: 351 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9539.91 Da        Isoelectric Point: 4.6683

>AT257970 WP_157318061.1 NZ_CP104467:c6598690-6598439 [Paenibacillus sp. SS4]
MISLPDNLLQEVDGIVEKENSNRSEFIRQAMKLYLIERKKRSLRESMQRGYMEMAKINLSMASEAFQAEEEADGTLDRLV
SGV

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1V4HIK6

Antitoxin

Source ID Structure

References