257922

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) hicAB/HicA(toxin)
Location 3564159..3564772 Replicon chromosome
Accession NZ_CP104408
Organism Pseudomonas fluorescens strain Ant01

Toxin (Protein)


Gene name hicA Uniprot ID A0A172Z267
Locus tag N4P55_RS16155 Protein ID WP_053256594.1
Coordinates 3564159..3564410 (+) Length 84 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag N4P55_RS16160 Protein ID WP_262665006.1
Coordinates 3564407..3564772 (+) Length 122 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N4P55_RS16155 (N4P55_16170) 3564159..3564410 + 252 WP_053256594.1 type II toxin-antitoxin system HicA family toxin Toxin
N4P55_RS16160 (N4P55_16175) 3564407..3564772 + 366 WP_262665006.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
N4P55_RS16165 (N4P55_16180) 3564755..3565945 - 1191 WP_221294967.1 MFS transporter -
N4P55_RS16170 (N4P55_16185) 3566088..3566681 + 594 WP_262665008.1 TetR/AcrR family transcriptional regulator -
N4P55_RS16175 (N4P55_16190) 3566665..3568020 - 1356 WP_064452749.1 MATE family efflux transporter -
N4P55_RS16180 (N4P55_16195) 3568046..3568618 - 573 WP_064452750.1 DUF2239 family protein -
N4P55_RS16185 (N4P55_16200) 3568686..3569642 - 957 WP_221294971.1 AAA family ATPase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(20-76)

Antitoxin

(55-105)


Sequences


Toxin        


Download         Length: 84 a.a.        Molecular weight: 9485.04 Da        Isoelectric Point: 9.6594

>T257922 WP_053256594.1 NZ_CP104408:3564159-3564410 [Pseudomonas fluorescens]
VSKNEKLLAKLLNEHMAFTWPELVTLLHRLGYTQIEGAGSRVKFDIGDPSAMISLHKPHPGNELKHYIRRQIIEQLKSGE
LIQ

Download         Length: 252 bp


Antitoxin


Download         Length: 122 a.a.        Molecular weight: 13283.25 Da        Isoelectric Point: 6.9477

>AT257922 WP_262665006.1 NZ_CP104408:3564407-3564772 [Pseudomonas fluorescens]
VNNQLKYKGYIGSIEASLEDNCLFGKILFIKALVSYEGKTVAELEAAFREAVDDYLATCHALGQTPEKPCKGSFNVRVGH
DLHLAAALAATRKKVTLNDLTRQALNEFLQHHCTEPLPVLG

Download         Length: 366 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A172Z267


Antitoxin

Source ID Structure

References