Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) shpAB/BrnT-BrnA
Location 651983..652559 Replicon chromosome
Accession NZ_CP104403
Organism Enterobacter hormaechei subsp. steigerwaltii strain csa13R

Toxin (Protein)


Gene name shpA Uniprot ID A0A800YKM1
Locus tag N5F14_RS03210 Protein ID WP_015572580.1
Coordinates 651983..652270 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID A0A801DSF4
Locus tag N5F14_RS03215 Protein ID WP_017694570.1
Coordinates 652257..652559 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5F14_RS03185 (N5F14_03185) 647076..647795 + 720 WP_050515874.1 winged helix-turn-helix domain-containing protein -
N5F14_RS03190 (N5F14_03190) 647945..648415 + 471 WP_033486706.1 MarR family transcriptional regulator -
N5F14_RS03195 (N5F14_03195) 648412..649479 + 1068 WP_026080654.1 HlyD family secretion protein -
N5F14_RS03200 (N5F14_03200) 649469..650545 + 1077 WP_015572578.1 DUF2955 domain-containing protein -
N5F14_RS03205 (N5F14_03205) 650542..651813 - 1272 WP_033486707.1 DUF445 domain-containing protein -
N5F14_RS03210 (N5F14_03210) 651983..652270 + 288 WP_015572580.1 BrnT family toxin Toxin
N5F14_RS03215 (N5F14_03215) 652257..652559 + 303 WP_017694570.1 BrnA antitoxin family protein Antitoxin
N5F14_RS03220 (N5F14_03220) 652588..653226 - 639 WP_033486708.1 LysE family translocator -
N5F14_RS03225 (N5F14_03225) 653265..654017 - 753 WP_033486709.1 AraC family transcriptional regulator -
N5F14_RS03230 (N5F14_03230) 654171..655541 + 1371 WP_133982341.1 NAD-dependent succinate-semialdehyde dehydrogenase -
N5F14_RS03235 (N5F14_03235) 655723..656268 - 546 WP_006810254.1 YfaZ family outer membrane protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(7-88)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(32-93)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11296.81 Da        Isoelectric Point: 7.3587

>T257884 WP_015572580.1 NZ_CP104403:651983-652270 [Enterobacter hormaechei subsp. steigerwaltii]
MPIEYEWDSNKAKSNLQKHAIRFEDAVLVFDDPCHLSVQDRYENGEFRWQTIGLVQGVIVILVAHTVRFESGDEIIRIIS
ARKADRKERRRYEHR

Download         Length: 288 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11482.13 Da        Isoelectric Point: 10.4094

>AT257884 WP_017694570.1 NZ_CP104403:652257-652559 [Enterobacter hormaechei subsp. steigerwaltii]
MSIVKHKRGSAPEVSARREAELKALADKPDREIDYSDIPATEDDRWAGAVRGKFYRPLKTQASVRIDADVMEWLKRPGKG
YQTRLNAILREAMLRDQNKK

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References