Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3892406..3893063 Replicon chromosome
Accession NZ_CP104401
Organism Enterobacter hormaechei subsp. steigerwaltii strain colR

Toxin (Protein)


Gene name cptA Uniprot ID A0A179PSF7
Locus tag N5F15_RS18775 Protein ID WP_017382887.1
Coordinates 3892406..3892816 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID G8LDB7
Locus tag N5F15_RS18780 Protein ID WP_003863437.1
Coordinates 3892797..3893063 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5F15_RS18755 (N5F15_18755) 3888404..3890137 - 1734 WP_017382886.1 single-stranded-DNA-specific exonuclease RecJ -
N5F15_RS18760 (N5F15_18760) 3890143..3890856 - 714 WP_033487627.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
N5F15_RS18765 (N5F15_18765) 3890885..3891781 - 897 WP_003863442.1 site-specific tyrosine recombinase XerD -
N5F15_RS18770 (N5F15_18770) 3891883..3892404 + 522 WP_015571793.1 flavodoxin FldB -
N5F15_RS18775 (N5F15_18775) 3892406..3892816 - 411 WP_017382887.1 protein YgfX Toxin
N5F15_RS18780 (N5F15_18780) 3892797..3893063 - 267 WP_003863437.1 FAD assembly factor SdhE Antitoxin
N5F15_RS18785 (N5F15_18785) 3893358..3894338 + 981 WP_047636517.1 tRNA-modifying protein YgfZ -
N5F15_RS18790 (N5F15_18790) 3894450..3895109 - 660 WP_003863433.1 hemolysin III family protein -
N5F15_RS18795 (N5F15_18795) 3895376..3896107 + 732 WP_015571796.1 MurR/RpiR family transcriptional regulator -
N5F15_RS18800 (N5F15_18800) 3896224..3896685 + 462 Protein_3672 family 1 glycosylhydrolase -
N5F15_RS18805 (N5F15_18805) 3896740..3897444 - 705 WP_001067855.1 IS6-like element IS26 family transposase -
N5F15_RS18810 (N5F15_18810) 3897511..3897744 - 234 Protein_3674 protein-disulfide reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16321.21 Da        Isoelectric Point: 11.4775

>T257878 WP_017382887.1 NZ_CP104401:c3892816-3892406 [Enterobacter hormaechei subsp. steigerwaltii]
VVLWQSDLRVSWRSQWMSLLLHGLVAALVLLVPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWEMMGTPWMLNTGMMLRLRRVEDNRRQHLWLAADSMDPAEWRDLRRLIVQQPTQE

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10526.96 Da        Isoelectric Point: 4.8310

>AT257878 WP_003863437.1 NZ_CP104401:c3893063-3892797 [Enterobacter hormaechei subsp. steigerwaltii]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
QERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A179PSF7

Antitoxin

Source ID Structure
AlphaFold DB A0A837F8P5

References