Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) shpAB/BrnT-BrnA
Location 680719..681295 Replicon chromosome
Accession NZ_CP104401
Organism Enterobacter hormaechei subsp. steigerwaltii strain colR

Toxin (Protein)


Gene name shpA Uniprot ID A0A800YKM1
Locus tag N5F15_RS03345 Protein ID WP_015572580.1
Coordinates 680719..681006 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID A0A801DSF4
Locus tag N5F15_RS03350 Protein ID WP_017694570.1
Coordinates 680993..681295 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5F15_RS03320 (N5F15_03320) 675812..676531 + 720 WP_050515874.1 winged helix-turn-helix domain-containing protein -
N5F15_RS03325 (N5F15_03325) 676681..677151 + 471 WP_033486706.1 MarR family transcriptional regulator -
N5F15_RS03330 (N5F15_03330) 677148..678215 + 1068 WP_026080654.1 HlyD family secretion protein -
N5F15_RS03335 (N5F15_03335) 678205..679281 + 1077 WP_015572578.1 DUF2955 domain-containing protein -
N5F15_RS03340 (N5F15_03340) 679278..680549 - 1272 WP_033486707.1 DUF445 domain-containing protein -
N5F15_RS03345 (N5F15_03345) 680719..681006 + 288 WP_015572580.1 BrnT family toxin Toxin
N5F15_RS03350 (N5F15_03350) 680993..681295 + 303 WP_017694570.1 BrnA antitoxin family protein Antitoxin
N5F15_RS03355 (N5F15_03355) 681324..681962 - 639 WP_033486708.1 LysE family translocator -
N5F15_RS03360 (N5F15_03360) 682001..682753 - 753 WP_033486709.1 AraC family transcriptional regulator -
N5F15_RS03365 (N5F15_03365) 682907..684277 + 1371 WP_133982341.1 NAD-dependent succinate-semialdehyde dehydrogenase -
N5F15_RS03370 (N5F15_03370) 684459..685004 - 546 WP_006810254.1 YfaZ family outer membrane protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(7-88)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(32-93)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11296.81 Da        Isoelectric Point: 7.3587

>T257866 WP_015572580.1 NZ_CP104401:680719-681006 [Enterobacter hormaechei subsp. steigerwaltii]
MPIEYEWDSNKAKSNLQKHAIRFEDAVLVFDDPCHLSVQDRYENGEFRWQTIGLVQGVIVILVAHTVRFESGDEIIRIIS
ARKADRKERRRYEHR

Download         Length: 288 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11482.13 Da        Isoelectric Point: 10.4094

>AT257866 WP_017694570.1 NZ_CP104401:680993-681295 [Enterobacter hormaechei subsp. steigerwaltii]
MSIVKHKRGSAPEVSARREAELKALADKPDREIDYSDIPATEDDRWAGAVRGKFYRPLKTQASVRIDADVMEWLKRPGKG
YQTRLNAILREAMLRDQNKK

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References