257855

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT_toxin-BrnA
Location 2733513..2733963 Replicon chromosome
Accession NZ_CP104386
Organism Cupriavidus gilardii strain WM02

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag N4G38_RS12920 Protein ID WP_232963065.1
Coordinates 2733513..2733626 (+) Length 38 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag N4G38_RS12925 Protein ID WP_252252901.1
Coordinates 2733610..2733963 (+) Length 118 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N4G38_RS12905 (N4G38_12905) 2729690..2730397 - 708 WP_174781321.1 two-component system response regulator CreB -
N4G38_RS12910 (N4G38_12910) 2730449..2731657 - 1209 WP_260730575.1 NAD(P)/FAD-dependent oxidoreductase -
N4G38_RS12915 (N4G38_12915) 2732131..2733312 + 1182 WP_198751423.1 benzoate/H(+) symporter BenE family transporter -
N4G38_RS12920 (N4G38_12920) 2733513..2733626 + 114 WP_232963065.1 hypothetical protein Toxin
N4G38_RS12925 (N4G38_12925) 2733610..2733963 + 354 WP_252252901.1 BrnA antitoxin family protein Antitoxin
N4G38_RS12930 (N4G38_12930) 2733971..2734831 + 861 WP_260730576.1 aminoglycoside 6-adenylyltransferase -
N4G38_RS12935 (N4G38_12935) 2734958..2735653 - 696 WP_252252903.1 TrkA family potassium uptake protein -
N4G38_RS12940 (N4G38_12940) 2735646..2736974 - 1329 WP_260730577.1 potassium transporter TrkG -
N4G38_RS12945 (N4G38_12945) 2737359..2737790 + 432 WP_053821272.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(27-107)


Sequences

Toxin        


Download         Length: 38 a.a.        Molecular weight: 4405.10 Da        Isoelectric Point: 9.2738

>T257855 WP_232963065.1 NZ_CP104386:2733513-2733626 [Cupriavidus gilardii]
IGTRLHCLIFTIRGDTLRAISLRKANFREVRDYEQEI

Download         Length: 114 bp

Antitoxin


Download         Length: 118 a.a.        Molecular weight: 12988.94 Da        Isoelectric Point: 10.6742

>AT257855 WP_252252901.1 NZ_CP104386:2733610-2733963 [Cupriavidus gilardii]
MNRKSKLTMPAADENAAIARGIADDPDAVELTTEQIKRMRPAREALAEVLGERNVEALIKRRGRPALPAAERKVSQTLRL
DPDVLQAFKATGDGWQTRINDALRAYAKSHRMLPRGC

Download         Length: 354 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References