Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 274841..275109 Replicon chromosome
Accession NZ_CP104371
Organism Escherichia coli strain 2021CK-01784

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 274968..275071 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 274841..275109 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N4502_RS01370 271394..272056 - 663 WP_000944256.1 exodeoxyribonuclease X -
N4502_RS01375 272080..272736 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein YobB -
N4502_RS01380 272838..273068 - 231 WP_000916763.1 DNA polymerase III subunit theta -
N4502_RS01385 273207..273581 + 375 WP_039720136.1 CopC domain-containing protein YobA -
N4502_RS01390 273585..274457 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
N4502_RS01395 274470..274811 + 342 WP_000976472.1 YebY family protein -
- 274841..275109 - 269 - - Antitoxin
- 274968..275071 + 104 - - Toxin
N4502_RS01400 275206..275862 + 657 WP_039720135.1 protein-serine/threonine phosphatase -
N4502_RS01405 275863..276054 - 192 WP_001296140.1 YebW family protein -
N4502_RS01410 276159..276395 - 237 WP_001295499.1 YebV family protein -
N4502_RS01415 276513..277952 - 1440 WP_039720143.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 267530..290949 23419
- inside Prophage - - 265667..290949 25282


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T257795 NZ_CP104371:274968-275071 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT257795 NZ_CP104371:c275109-274841 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References